[Animal Modeling] - Establishment of a Model of Influenza Virus Infection Secondary to Streptococcus Pneumoniae Pneumonia

In the ranking of mortality rates for human diseases, bacterial pneumonia and influenza rank sixth. Animal models can be used to study the mechanism of the interaction between influenza and pneumococcus...

2023-09-26

[Animal Modeling] - Establishment of a Model of Streptococcus Pneumoniae Secondary to Metapulmonary Virus Infection

Modeling method: HMPV strain C-85473 was cultured with LLC-MK2, and female BALB/c mice were cultured with 1.5 × HMPV nasal drip infection with a dose of 100000 TCID50, followed by pneumococcal nasal drip infection with a dose of 1000 cfu after 5 days...

2023-09-26

[Animal Modeling] - Autologous White Thrombotic Monkey Model of Local Cerebral Ischemia

Model material animal: Crab eating monkey, male, weighing 6-8kg, aged 6-8 years old, preoperative CT plain scan, excluding brain space occupying lesions; Drugs: Ketamine hydrochloride, diazepam, scopolamine, propofol, thrombin, etc...

2023-09-26

【Animal Model】- Rat model of chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a chronic respiratory system disease. Its airflow limitation is characterized by inflammation and the concentrated effect of the lungs on harmful gases (such as cigarette smoke and harmful particles (es...

2023-09-26

[Animal Modeling] - In vivo Thrombosis Animal Model

Animal modeling material: Wistar rats, male and female, weighing 200-250g; Medication: Ethyl carbamate, heparin injection; Equipment: Disposable intravenous indwelling needle, BL-420 biological function experimental system...

2023-09-26

[Animal Modeling] - A Simple Model of Lung Qi Deficiency Syndrome in Mice

Reproduction method: Adult mice were stimulated with cigarette smoke at a dose of 2 cigarettes per 10 mice each time. The lit cigarettes were fixed in a transparent glass bell and the model mice were placed in it twice a day for 12 minutes each time ...

2023-09-26

[Animal Modeling] - Animal Model of Lung Qi Deficiency Syndrome by Smoking Method

Reproduction method: Adult rats or rabbits were placed in a smoke chamber with a volume of 1m3. 30-50g of shavings, sawdust, and tobacco were ignited and smoked once a day for 30 minutes each time. The smoking time of the rabbits was doubled, and the...

2023-09-26

[Animal Modeling] - Oxazolone Colitis Mouse Model

Animal model material: BALC/c mice, 7-8 weeks old, weighing 25-30g; Medications: Oxazolidone, Mizumab, Ethanol...

2023-09-26

[Animal Modeling] - Animal Model of Spleen Dysfunction Syndrome with Gastric Infusion of Wine, Vinegar, and Aspirin

Reproduction method: Adult rats were given a dose of 50% medical ethanol 1ml/100g body weight by gavage on the 1st day, Baoning vinegar 1ml/100g body weight by gavage on the 2nd to 11th day, and 1% aspirin 1ml/100g body weight by gavage on the 12th t...

2023-09-26

【Animal Model】-Long-term effects of sublethal dose of γ-ray whole body irradiation on hematopoietic immune function in mice

To observe the changes of hematopoietic and immune function indexes in C57BL/6J mice 6 months after total body irradiation with 4Gy and 6Gy...

2023-09-25

【Animal Modeling】-Measurement and Significance of Noninvasive Pulmonary Function in Mice

To detect non-invasive pulmonary function indexes in C57BL/6 mice, and to provide a basis for the monitoring of pulmonary function in experimental studies in mice...

2023-09-25

[Animal modeling] - Animal experimental study on two different types of left atrial appendage occluders

To evaluate the feasibility and safety of left atrial appendage (LAA) closure with single disc cylindrical occluder and double disc split occluder...

2023-09-25

【Animal Modeling】-Establishment of a Drosophila Heart Failure Model Induced by High-fat Diet

To establish a model of Drosophila heart failure induced by high-fat diet...

2023-09-25

【Animal Modeling】 - Severe Combined Immunodeficiency Mouse Chronic Colitis Model

Female BALB/c mice (H-2 gene phenotype), aged 8-10 weeks at the time of use; Reagents and antibodies: Hamster anti mouse CD3 monoclonal antibody, fluorescein isothiocyanate labeled anti mouse CD45RB monoclonal antibody, phycoerythrin (PE) labeled ant...

2023-09-22

【 Animal modeling 】 -2,4,6-trinitrobenzene sulfonic acid induced ulcerative colitis model in rats

Animal modeling materials: 42 male SD rats, weighing (200 ± 20) g; Medication: 2,4,6-trinitrobenzenesulfonic acid...

2023-09-22

[Animal modeling] - Animal experimental evaluation on the safety pharmacology of Tanreqing injection

To observe the effects of Tanreqing injection on cardiovascular system, respiratory system of Beagle dogs and central nervous system of ICR mice, and to provide experimental data for its safety in clinical use...

2023-09-22