【Animal Modeling】-Mechanism of platelets in salt-sensitive hypertension through inflammatory response

To investigate the role and molecular mechanism of platelets in high-salt-induced salt-sensitive hypertension...

2022-11-16

【Animal modeling】-The regulatory effect of Wuji pills on brain-gut peptides in rats with post-inflammatory irritable bowel syndrome

To find biological indicators for the diagnosis and treatment of irritable bowel syndrome (IBS)....

2022-11-16

【Animal Modeling】-Aniline-induced DNA damage in mouse hepatocytes and lymphocytes and its repair effect

To study the genotoxicity of aniline and its repair kinetics...

2022-11-16

[Animal modeling] Preventive and therapeutic effects of diaminazine in rats with pulmonary hypertension

To investigate the preventive and therapeutic effects of diaminazine (DIZE) on pulmonary hypertension (PAH) in rats...

2022-11-16

【Animal modeling】-Effect of Lycium barbarum polysaccharide on tumor growth and metastasis in spontaneous breast cancer MMTV-PyMT mice

To investigate the effect of Lycium barbarum polysaccharide on the growth and metastasis of breast cancer using MMTV-PyMT mice as a breast cancer model...

2022-11-15

【Animal Modeling】-The damage characteristics of olfactory working memory in the very early stage of Alzheimer\\

To investigate the characteristics of olfactory working memory impairment in the very early stage of Alzheimer\\\'s disease transgenic mice...

2022-11-15

【Animal Modeling】-Effect of intrauterine injection of absolute ethanol on estrous cycle in mice

To investigate the effect of intrauterine injection of absolute ethanol on the estrous cycle of mice...

2022-11-15

【Animal Modeling】-How to establish a mouse model of alcoholic cardiomyopathy?

Establish a mouse alcoholic cardiomyopathy model through a liquid diet to provide an excellent animal model for studying the pathogenesis of alcoholic cardiomyopathy...

2022-11-14

【Animal Modeling】-Effect of hydrogen sulfide on myocardial fibrosis and expression of MAPK1/3 and MMP-8 in diabetic rats

To investigate the effect of gas signal molecule hydrogen sulfide (H2S) on myocardial fibrosis and protein expression of MAPK1/3 and MMP-8 in diabetic rats...

2022-11-14

【Animal modeling】-The neuroprotective effect of artesunate on experimental autoimmune encephalomyelitis mice and the effect of autophagy

To investigate the neuroprotective effect and autophagy of artesunate on experimental autoimmune encephalomyelitis (EAE) mice...

2022-11-14

【Animal Modeling】-Interventional effect of flavonoids in Sandianjin on ulcerative colitis mice and their effects on intestinal flora

To investigate the intervention effect of the national medicine Sandianjin total flavonoids and its monomer compounds vervasoflavone and formononetin on dextran sodium sulfate (DSS)-induced ulcerative colitis (UC) mice. Influence of gut microbiota...

2022-11-14

【Animal Modeling】-Preliminary study on the structural and functional differences of reproductive system between fertile and infertile male naked mole rats

To observe and analyze the differences in reproductive system structure and function between fertile and infertile male naked mole-rats, and preliminarily explore the reasons why male infertile individuals cannot reproduce...

2022-11-14

【Animal modeling】-Combined with high-resolution MRI and micro-CT to evaluate the repairing effect of Taohong Siwu Decoction on femoral head necrosis in rabbits

To establish a rabbit model of steroid-induced necrosis of the femoral head (SIONFH), and to evaluate the repairing effect of Taohong Siwu Decoction (THSWD) on the damage of SIONFH microscopic bony structure combined with high-resolution MRI and micr...

2022-11-14

【Animal modeling】-Effect of camel milk on glucose and lipid metabolism and PPAR-γ, TNF-α mRNA in type 2 diabetic rats

To study the effects of camel milk (CM) on body weight, blood glucose, blood lipids, insulin, PPARγ and TNF-α gene expression in type 2 diabetic rats...

2022-11-14

【Animal modeling】-Safety evaluation of Japanese white rabbit skin irradiated by light-emitting diode light source

To irradiate the skin tissue of Japanese white rabbit with LED white light source, and to preliminarily evaluate the safety of LED light source irradiation...

2022-11-14

【Animal modeling】-The effect of 6-week free runner exercise on sex hormones and hypothalamic-pituitary-testis axis in high-fat-fed male rats

To observe the effect of high-fat diet on the structure of hypothalamus, pituitary, testis and sex hormone levels in adolescent male rats, and to explore the intervention effect of 6-week free wheel exercise...

2022-11-14