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【Animal Modeling】Effect of -60Coγ-ray radiation on the spleen of naked mole rats

【Animal Modeling】Effect of -60Coγ-ray radiation on the spleen of naked mole rats

To observe the changes of spleen immune system and tissue biochemical indexes in naked mole-rats after 60Co γ-ray irradiation, and to preliminarily understand the radiation tolerance characteristics of naked mole-rats spleen...

2022-05-07
【Animal modeling】-Prnp-SNCA-A53T Parkinson\'s disease transgenic mice with different intestinal flora

【Animal modeling】-Prnp-SNCA-A53T Parkinson\'s disease transgenic mice with different intestinal flora

A number of evidences indicate that the intestinal flora of Parkinson\'s disease patients is abnormal, and whether Prnp-SNCA-A53T Parkinson\'s disease transgenic mice also have intestinal flora dysbiosis has not been reported. Microbial ecological ch...

2022-05-07
【Animal Modeling】-Expression and distribution of protein degradation pathway regulatory molecules in mouse nervous system

【Animal Modeling】-Expression and distribution of protein degradation pathway regulatory molecules in mouse nervous system

To investigate the expression and distribution of regulatory molecules of cellular protein degradation pathway in mouse nervous system...

2022-05-06
【Animal modeling】-Isolation and identification of exosomes from skin fibroblasts of naked mole rats

【Animal modeling】-Isolation and identification of exosomes from skin fibroblasts of naked mole rats

To isolate and culture naked mole rat skin fibroblasts, identify them, and explore whether naked mole rat skin fibroblasts have the ability to secrete exosomes...

2022-05-06
【Animal Modeling】-miR-122 Expression Changes and Action Mechanisms in Kidney Tissues of Mice with Diabetic Nephropathy

【Animal Modeling】-miR-122 Expression Changes and Action Mechanisms in Kidney Tissues of Mice with Diabetic Nephropathy

To investigate the expression changes of miR-122 in the kidney tissue of diabetic nephropathy mice and the effect and possible mechanism of silencing miR-122 on the kidney tissue of DN mice...

2022-05-06
【Animal Modeling】-Changes in the structure and function of the immune system of SD rats during natural aging

【Animal Modeling】-Changes in the structure and function of the immune system of SD rats during natural aging

To observe the changes in the structure and function of the immune system in naturally aged SD rats, and to explore the possible mechanisms?...

2022-05-06
【Animal Modeling】-Optimization of PCR detection method for Pasteurella pneumophila in mice and its preliminary application in different sample processing

【Animal Modeling】-Optimization of PCR detection method for Pasteurella pneumophila in mice and its preliminary application in different sample processing

To establish a real-time, rapid, sensitive and simple PCR method for the detection of Pasteurella pneumophila in living experimental animals...

2022-05-06
【Animal Modeling】-Small ubiquitin-like modifier protease 3 regulates autophagy in mouse alveolar type II epithelial cells

【Animal Modeling】-Small ubiquitin-like modifier protease 3 regulates autophagy in mouse alveolar type II epithelial cells

To investigate the regulatory effect and molecular mechanism of small ubiquitin-like modifier-specific protease 3 on autophagy in mouse lung tissue...

2022-05-06
【Animal modeling】-Validation of the effect of SPF golden hamster cage and drinking water pulsed vacuum sterilization

【Animal modeling】-Validation of the effect of SPF golden hamster cage and drinking water pulsed vacuum sterilization

To confirm the performance of the pulse vacuum sterilizer, and to verify the effect of pulse vacuum sterilization on the SPF golden hamster cage and drinking water under the specified loading method and sterilization conditions...

2022-05-06
【Animal modeling】-Comparative analysis of single nucleotide polymorphisms and alternative splicing before and after vitrification of bovine blastocysts

【Animal modeling】-Comparative analysis of single nucleotide polymorphisms and alternative splicing before and after vitrification of bovine blastocysts

【Animal Modeling】-Comparative Study on Fine Behavior of Mouse Spinal Cord Injury Strike Model...

2022-05-05
【Animal Modeling】-Comparative Study on Fine Behavior of Mouse Spinal Cord Injury Strike Model

【Animal Modeling】-Comparative Study on Fine Behavior of Mouse Spinal Cord Injury Strike Model

To investigate the abnormal performance of fine behaviors in home cages, such as voluntary movement, exploratory behavior and self-care behavior, in addition to motor dysfunction in mice with spinal cord injury...

2022-05-05
【Animal Modeling】-Influencing Factors in the Analysis of Serum Glucose in Rats

【Animal Modeling】-Influencing Factors in the Analysis of Serum Glucose in Rats

To investigate the influencing factors of serum glucose measurement and analysis in rats...

2022-05-05
【Animal modeling】-CD137 signaling regulates endothelial cell-mesenchymal transition and promotes cardio-cerebral angiogenesis in mice

【Animal modeling】-CD137 signaling regulates endothelial cell-mesenchymal transition and promotes cardio-cerebral angiogenesis in mice

To investigate whether CD137-CD137L signal (CD137 signal for short) promotes cardio-cerebral angiogenesis by regulating endothelial cell-mesenchymal transition...

2022-05-05
【Animal Modeling】-Manufacture and use of a mouse hindlimb acupuncture fixation device

【Animal Modeling】-Manufacture and use of a mouse hindlimb acupuncture fixation device

To make a simple fixation device for acupuncture on the hindlimb of mice, and to provide an economical, practical, convenient and efficient tool for acupuncture experimental operation...

2022-05-05
【Animal modeling】-Dynamic changes of myocardial fibrosis time series in spontaneously hypertensive rats

【Animal modeling】-Dynamic changes of myocardial fibrosis time series in spontaneously hypertensive rats

Observation of temporal dynamic changes of myocardial fibrosis in spontaneously hypertensive rats...

2022-05-05
【Animal Modeling】-Analysis of Intestinal Microorganisms in Miniature Pig Type 2 Diabetes Model

【Animal Modeling】-Analysis of Intestinal Microorganisms in Miniature Pig Type 2 Diabetes Model

Recent studies have shown that gut microbes are associated with metabolic diseases such as type 2 diabetes mellitus (T2DM), and the related mechanisms are mostly studied in rodents, but there are few reports on pig models that are more suitable for s...

2022-05-05