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【Animal modeling】-Echocardiographic evaluation of cardiac structure and function changes after acute myocardial ischemia injury in rats

【Animal modeling】-Echocardiographic evaluation of cardiac structure and function changes after acute myocardial ischemia injury in rats

To evaluate the changes of cardiac structure and function in rats after acute myocardial ischemia injury by echocardiography...

2022-04-23
【Animal modeling】-Mechanism of transient receptor potential channel C1 in airway remodeling in guinea pig asthma and the intervention effect of budesonide

【Animal modeling】-Mechanism of transient receptor potential channel C1 in airway remodeling in guinea pig asthma and the intervention effect of budesonide

To explore the mechanism of TRPC1 ion channel in the evolution of airway remodeling and the intervention effect of budesonide by interfering with the expression of transient receptor potential channel C1 (TRPC1)...

2022-04-22
【Animal modeling】-Construction of MiR-31 transgenic mice and its expression in tissues and organs

【Animal modeling】-Construction of MiR-31 transgenic mice and its expression in tissues and organs

To construct stably overexpressed miR-31 transgenic mice, to detect the expression changes of miR-31 in major tissues and organs, and to provide qualified tool mice for the application of miR-31 overexpression in vivo...

2022-04-22
【Animal modeling】-Establishment of ELISA detection method for mouse anti-rabies virus IgG antibody

【Animal modeling】-Establishment of ELISA detection method for mouse anti-rabies virus IgG antibody

To establish a mouse anti-rabies virus IgG antibody ELISA method for the detection and analysis of rabies mouse model...

2022-04-22
【Animal Modeling】-Isoproterenol-induced angina pectoris animal model

【Animal Modeling】-Isoproterenol-induced angina pectoris animal model

Isoproterenol is a catecholamine-based drug, which is a β-adrenergic receptor agonist, which can increase myocardial contraction and oxygen consumption, thereby increasing myocardial burden and myocardial microcirculation, and causing myocardial dama...

2022-04-22
[Animal modeling]-Myocardial regeneration occurs only on the first day after the mouse is born

[Animal modeling]-Myocardial regeneration occurs only on the first day after the mouse is born

Scientists claim to observe myocardial regeneration in newborn mice. Then they reported that after a piece of the small heart of the newborn mouse was cut, the heart muscle would regenerate. This is a self-repair....

2022-04-22
【Animal Modeling】-Miniature Pig Pulpitis Model

【Animal Modeling】-Miniature Pig Pulpitis Model

Experimental method There are 5 piglets weighing 14 to 26 kg in China, 3 males and 2 females. Select upper and lower first permanent molars and bilateral incisors to create a pulpitis model...

2022-04-22
【Animal Modeling】-Analysis of single nucleotide polymorphisms and alternative splicing before and after freezing blastocysts of bovine cattle based on RNA-Seq technology

【Animal Modeling】-Analysis of single nucleotide polymorphisms and alternative splicing before and after freezing blastocysts of bovine cattle based on RNA-Seq technology

To compare and analyze the single nucleotide polymorphisms and alternative splicing of bovine blastocysts before and after vitrification...

2022-04-21
【Animal modeling】-Changes of C-reactive protein and inflammatory factors in Pterima pig model of plateau multiple organ dysfunction syndrome

【Animal modeling】-Changes of C-reactive protein and inflammatory factors in Pterima pig model of plateau multiple organ dysfunction syndrome

To study the changes of tumor necrosis factor-α, interleukin-1β and C-reactive protein in the process of inflammatory reaction in the Phenma pig model of plateau multiple organ dysfunction syndrome...

2022-04-21
【Animal Modeling】-Rat Lumbar Spinal Canal Stenosis Model

【Animal Modeling】-Rat Lumbar Spinal Canal Stenosis Model

Reproduction method Anesthetize rats by intraperitoneal injection of phenobarbital at 50 mg/kg body weight...

2022-04-20
【Animal Modeling】- Improvement and effect evaluation of tracheal instillation in rats

【Animal Modeling】- Improvement and effect evaluation of tracheal instillation in rats

To establish a non-invasive tracheal instillation method for rats with visual, simple, rapid and precise instillation...

2022-04-20
【Animal Modeling】-Atherosclerosis model of insulin resistance in white-haired black-eyed rabbits and Japanese big-eared white rabbits

【Animal Modeling】-Atherosclerosis model of insulin resistance in white-haired black-eyed rabbits and Japanese big-eared white rabbits

To investigate the phenotypic differences and pathological mechanisms of insulin resistance atherosclerosis models in white-haired black rabbits and Japanese big-eared white rabbits...

2022-04-20
【Animal Modeling】-Analysis of Factors Affecting the Production Efficiency of Bacterial Artificial Chromosome Transgenic Mice

【Animal Modeling】-Analysis of Factors Affecting the Production Efficiency of Bacterial Artificial Chromosome Transgenic Mice

To compare several key factors in the development of bacterial artificial chromosome transgenic mice, such as the genetic background of experimental mice, BAC plasmid injection concentration, BAC plasmid fragment size and BAC injection storage time,...

2022-04-20
【Animal modeling】-The role of CaN-NFATc3 pathway in restenosis after balloon dilation of abdominal aorta in rats

【Animal modeling】-The role of CaN-NFATc3 pathway in restenosis after balloon dilation of abdominal aorta in rats

To study the role of calcineurin (CaN) and its downstream activated T cell nuclear factor (NFATc3) in restenosis after balloon dilation, and to provide a new theoretical basis for the prevention and treatment of vascular restenosis...

2022-04-20
【Animal Modeling】-Comparison of the difference of glutamate-induced swelling of cultured astrocytes between two varieties of rats

【Animal Modeling】-Comparison of the difference of glutamate-induced swelling of cultured astrocytes between two varieties of rats

To compare the differences of glutamate-induced cell swelling by cultured astrocytes (AST) in Wistar rats and SD rats...

2022-04-20
【Animal modeling】-Comparative study on bone growth in rats after long-term exposure to low-fluoride aluminum and short-term high-fluoride aluminum exposure

【Animal modeling】-Comparative study on bone growth in rats after long-term exposure to low-fluoride aluminum and short-term high-fluoride aluminum exposure

To observe the effects of different doses of fluoride and aluminum combined with the duration of intake on longitudinal bone growth and bone metabolism in rats...

2022-04-18