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【Animal modeling】-Protective effect of GDF11 on myocardial injury in type II diabetic mice

【Animal modeling】-Protective effect of GDF11 on myocardial injury in type II diabetic mice

To observe the protective effect of GDF11 on myocardial injury in C57BL/6J mice with type Ⅱ diabetes mellitus and the changes of myocardial apoptosis...

2022-01-24
【Animal modeling】-Expression and purification of Asprosin and its effect on mouse cardiac function in vivo

【Animal modeling】-Expression and purification of Asprosin and its effect on mouse cardiac function in vivo

To express and purify asprosin protein in prokaryotic cells of Escherichia coli, and to study its effect on the improvement of cardiac function...

2022-01-24
【Animal modeling】-Micro-CT observation of the effect of recombinant human parathyroid hormone on fracture healing in 2-month-old male rats

【Animal modeling】-Micro-CT observation of the effect of recombinant human parathyroid hormone on fracture healing in 2-month-old male rats

Using Micro-CT to investigate the role of recombinant human parathyroid hormone (rhPTH) in fracture healing in 2-month-old male rats...

2022-01-24
【Animal modeling】-Effect of sugar supplementation on the activation of adenosine monophosphate-activated protein kinase in the myocardium of acute exercise rats

【Animal modeling】-Effect of sugar supplementation on the activation of adenosine monophosphate-activated protein kinase in the myocardium of acute exercise rats

To investigate the effect of sugar supplementation on the activation of AMPK in exercise myocardium by measuring the changes in myocardial adenosine monophosphate-activated protein kinase activity and glycogen content after acute exercise in rats...

2022-01-24
【Animal Modeling】-Comparison of Ulcer Wound Healing in Two Type 2 Diabetic Mice

【Animal Modeling】-Comparison of Ulcer Wound Healing in Two Type 2 Diabetic Mice

To compare the healing characteristics of ulcer wounds in C57BL/6J-db/db and STZ-induced C57BL/6J mice with type 2 diabetes mellitus commonly used, and to conduct relevant animal experiments for the application of a stable diabetic mouse ulcer model ...

2022-01-24
【Animal Modeling】-Effect of air balloon on the results of abdominal wall withdrawal reflex experiment

【Animal Modeling】-Effect of air balloon on the results of abdominal wall withdrawal reflex experiment

To optimize the appropriate materials for the preparation of balloons for abdominal wall withdrawal reflex experiments...

2022-01-24
【Animal Modeling】-Effects of different frequencies of music on spatial learning and memory in mice

【Animal Modeling】-Effects of different frequencies of music on spatial learning and memory in mice

To preliminarily explore whether music affects the learning and memory ability of adult mice...

2022-01-24
【Animal Modeling】-Discussion on Influencing Factors of Non-Human Primate Evaluation of Learning and Memory Function

【Animal Modeling】-Discussion on Influencing Factors of Non-Human Primate Evaluation of Learning and Memory Function

The delayed response test based on the Wisconsin Universal Tester is a common method to evaluate the learning and memory ability of non-human primates. The experiment is affected by many factors during the process. The learning and memory ability has...

2022-01-24
【Animal modeling】-Effect of rhubarb root extract on the morphology of tissues and organs in mice with experimental psoriasis

【Animal modeling】-Effect of rhubarb root extract on the morphology of tissues and organs in mice with experimental psoriasis

To investigate the effect of rhubarb root extract on the morphology of tissues and organs in experimental psoriasis model mice...

2022-01-24
【Animal Modeling】-Effect of SEL1L gene deletion in central neurons on mouse behavior

【Animal Modeling】-Effect of SEL1L gene deletion in central neurons on mouse behavior

To explore the role of endoplasmic reticulum protein SEL1L in maintaining normal physiological activities of mammalian central nervous system...

2022-01-24
【Animal Modeling】-Comparison of Different Methods of Inducing THP-1 Cell Differentiation

【Animal Modeling】-Comparison of Different Methods of Inducing THP-1 Cell Differentiation

To optimize different methods to stimulate the directional differentiation of THP-1 cells into M1, M2 macrophages and DC cells, and lay the foundation for the study of three in vitro cell models of M1, M2 and DC...

2022-01-24
【Animal modeling】The effect of -1α,25(OH)2D3 on the expression of lubricin in rat articular chondrocytes

【Animal modeling】The effect of -1α,25(OH)2D3 on the expression of lubricin in rat articular chondrocytes

To investigate the effect of 1α,25(OH)2D3 on the synthesis and secretion of lubricin in chondrocytes at the cellular level...

2022-01-24
【Animal modeling】-Flow cytometry analysis of the phenotypic characteristics of PMA-induced THP-1 differentiation into macrophages

【Animal modeling】-Flow cytometry analysis of the phenotypic characteristics of PMA-induced THP-1 differentiation into macrophages

To clarify the differentiation of macrophages derived from THP-1 cells induced by PMA alone by flow cytometry...

2022-01-24
[Animal Modeling]-Intervention of Electroacupuncture on NF-κBp65 Protein in the Spinal Dorsal Horn of Rats with Diabetic Neuralgia

[Animal Modeling]-Intervention of Electroacupuncture on NF-κBp65 Protein in the Spinal Dorsal Horn of Rats with Diabetic Neuralgia

To observe the effect of electroacupuncture on p65 protein in the posterior horn of spinal cord in rats with diabetic neuralgia, and to explore the local analgesic effect of electroacupuncture on diabetic neuralgia...

2022-01-22
【Animal Modeling】-The effect of inflammatory factor storm on the immune response to infection in old mice

【Animal Modeling】-The effect of inflammatory factor storm on the immune response to infection in old mice

After highly pathogenic avian influenza infects mice, over-expressed inflammatory factors, i.e. inflammatory factor storm, are detected in the lungs...

2022-01-22
【Animal Modeling】-Construction and application of an improved animal model of rat skull defect

【Animal Modeling】-Construction and application of an improved animal model of rat skull defect

Explore an ideal method for establishing a rat skull defect model and increase the success rate of animal models of bone defect...

2022-01-22