[Animal model]-After rats become addicted to cocaine, their offspring become more addictive

Will drug use affect the health of future generations? Professor Ma Lan of the Institute of Brain Science of Fudan University and the National Institute of Medicine and Neurobiology said that the first and second generation offspring of cocaine addic...

2020-09-02

[Animal model]-A new generation of miniaturized two-photon fluorescence microscope\" was successfully developed, and it may be possible to observe animal brains in the process of free behavior

Micro two-photon fluorescence microscopy imaging technology has changed the way we observe cell and subcellular structures in freely moving animals...

2020-09-02

【Animal Experiment】-Lentivirus-mediated construction of stable knockdown Smurf1 cell line and its effect on cell migration

Construct HeLa and A549 cell lines that can knock down Smurf1 stably by lentivirus, and test the effect of knockdown on Smurf1 cell migration...

2020-09-02

【Animal Experiment】-The protective effect of nimodipine on PC12 cell apoptosis induced by H2O2

To explore the protective effect of nimodipine on the apoptosis of PC12 cells induced by hydrogen peroxide (H2O2)...

2020-09-02

[Animal Experiment]-The effect of microinjection of K252a into the hippocampus on rat behavior and depression-like classic indicators

Microinject K252a into the hippocampus to study its effect on rat behavior and classic depression-like indicators, and establish a new depression model...

2020-09-02

【Animal Experiment】-Experimental study on the formation mechanism of rabbit dural arteriovenous fistula caused by high intracranial pressure

Dural arteriovenous fistula (DAVF) refers to an abnormal connection between an artery and the meninges or dural sinuses or cortical veins. This is an intracranial vascular malformation. Dural arteriovenous fistula accounts for about 10% to 15% of int...

2020-09-02

【Animal Experiment】-Researchers have proposed that genetically modified bacteria in experimental mice may become a powerful weight loss tool in the future

In the United States, more than one-third of adults are obese, obesity is difficult to treat with medication, and due to the serious side effects of weight-loss drugs, many drugs are not available...

2020-09-01

New mouse AD model experiments suggest that the efficacy of bexarotene in the treatment of AD depends on the stage of AD disease

The cancer drug bexarotene (bexarotene) has shown therapeutic effects in mice with Alzheimer\'s disease, but it has obtained confusing results in a new mouse model of AD (bexarotene). As a result, bexarotene is a mouse with advanced Alzheimer’s disea...

2020-09-01

[Animal Experiment]-New Gospel for Diabetic Patients FGF1 protein can efficiently restore blood glucose levels in mice

Mouse diabetes induced by mouse diet is equivalent to human type 2 diabetes. A new study found that a single injection of FGF1 protein is enough to restore the blood glucose level of mice to the normal range, and this effect of FGF1 lasted for more t...

2020-09-01

【Animal Experiment】-University of Colorado research in laboratory rats shows that antioxidants can restore vitality to the aged arteries

Recent studies have shown that antioxidants targeting specific cytoskeleton mitochondria can mask certain side effects of arterial aging and reduce the risk of heart disease...

2020-09-01

Confirmed that miRNA can inhibit the apoptosis of nerve cells induced by methylmalonic acid

Methylmalonic acidemia (MMA) is a metabolic disease caused by the lack of mitochondrial enzyme malonate-CoA mutant enzyme...

2020-09-01

[Animal experiment]-Chinese and American researchers found that acute glaucoma in mice is an inflammatory disease

Recently, researchers in China and the United States discovered that acute glaucoma in mice is an inflammatory disease. Increased intraocular pressure or inflammation leading to blindness...

2020-09-01

[Animal Experiment]-USC scientists use TRAP technology to capture early signs of acute kidney injury in mice

Recently, USC stem cell scientists have successfully established a signal capture mouse (TRAPmouse) for acute kidney injury...

2020-09-01

[Animal experiment]-Southern Medical University found that knockout of α-synuclein protects dopaminergic neurons in Parkinson\'s disease model rats

In the methamphetamine-induced Parkinson\'s disease model, the overexpression of α-synuclein is the main cause of death of dopaminergic neurons....

2020-09-01

[Animal experiment]-Mouse intestinal experiment reveals a new computer model or can monitor the dynamics of the intestinal flora after infection

Recently, in a research paper published in the international journal PLoSONE, researchers at Brigham and Women’s Hospital often feel uncomfortable due to infections and use special computer models to make infections more natural...

2020-09-01

[Animal Experiment]-Scientists extend the preservation time of rat liver for transplantation

Thanks to the efforts of scientists, the preservation and preservation period of rat liver used for organ transplantation has been significantly extended to 4 days. A study published in \"Natural Medicine\" found that it may directly solve ...

2020-09-01