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How to prepare an animal model of linear impact accelerated head injury?

How to prepare an animal model of linear impact accelerated head injury?

The model was established by Marmarou in 1994. The specific steps for creating the model are: put a prone rat on a foam pad and cut the skin longitudinally to expose the skull...

2020-08-11
How to prepare an animal model of chronic exercise fatigue?

How to prepare an animal model of chronic exercise fatigue?

Replication method Use SD male rats weighing 200-220g, and use a high-intensity treadmill for 7 weeks from the first week of training. The weekly speed is increased to 15m/min, 22m/min, 27m/min, 31m/min. , 35m/min. We will train 5 days a week, 20 min...

2020-08-11
How to prepare an animal model of hypersplenism?

How to prepare an animal model of hypersplenism?

Obesity is a clinical syndrome and one of the most common symptoms in patients with liver cirrhosis. The main clinical symptom is splenomegaly, in which one or more types of blood cells are depleted and bone marrow hematopoietic cells proliferate. Th...

2020-08-10
How to prepare an animal model of diffuse intravascular coagulation?

How to prepare an animal model of diffuse intravascular coagulation?

Disseminated intravascular coagulation (diffuse intravascular coagulation syndrome, DIC) is a clinically acquired syndrome that may be caused by many reasons...

2020-08-10
How to prepare an animal model of hyperlipidemia?

How to prepare an animal model of hyperlipidemia?

Reproduction method In addition to normal feeding conditions, use male KM mice weighing about 35g, using a fat emulsion (fat emulsion) at a dose of 10ml/kg body weight. Management Preparation: Put 80g of lard into a 500ml beaker and dissolve it in an...

2020-08-10
How to prepare animal model of platelet disease?

How to prepare animal model of platelet disease?

Most patients with idiopathic thrombocytopenic purpura (idiopathic thrombocytopenic purpura, ITP) do not have a clear exogenous pathogen, and are detected by antiplatelet antibodies in the blood, and are also related to idiopathic self Immune platele...

2020-08-10
How to prepare animal models of leukocyte disease?

How to prepare animal models of leukocyte disease?

Attenuation studies used to study the toxicity of chemotherapy drugs usually require the establishment of animal models of chemotherapy-induced leukopenia and myelopenia...

2020-08-10
How to prepare an animal model of aplastic anemia?

How to prepare an animal model of aplastic anemia?

Clinically, aplastic anemia (AA) is a group of hematopoietic tissue failure syndromes. Most patients are middle-aged and the prognosis of acute cases is poor...

2020-08-10
How to prepare an animal model of hemolytic anemia?

How to prepare an animal model of hemolytic anemia?

Hemolytic anemia is a group of anemias that occurs when the destruction of red blood cells increases and the speed exceeds the compensatory capacity of hematopoietic function. When the average life span of red blood cells is 15 to 20 days, and the de...

2020-08-10
How to prepare animal model of hemorrhagic anemia?

How to prepare animal model of hemorrhagic anemia?

Blood loss is one of the most common causes of anemia in the body and is clinically divided into acute and chronic. Chronic blood loss often causes iron deficiency anemia. Anemia caused by blood vessel rupture or poor hemostatic mechanism caused by t...

2020-08-10
How to prepare animal models of hypertrophic scars and keloids?

How to prepare animal models of hypertrophic scars and keloids?

The normal healing of human and animal skin injury ends in leaving small and superficial scars. Hypertrophic scars (HS) and keloids are only found in humans and can cause changes in appearance and dysfunction....

2020-08-10
How to prepare a skin allergy animal model?

How to prepare a skin allergy animal model?

Breeding methods: White guinea pigs weighing 200 to 250 g and 4 to 5 weeks old are sensitized on the 1st and 8th days, and challenged on the 15th day...

2020-08-10
How to prepare animal models of myositis?

How to prepare animal models of myositis?

Polymyositis is a common autoimmune disease in neuromuscular diseases,Abnormal cellular and humoral immunity play an important role in the destruction of muscle tissue...

2020-08-10
How to prepare a frostbite animal model?

How to prepare a frostbite animal model?

Frostbite is a symptom of damage to certain parts of the body that are affected by a cold. The freezing method includes immersing rabbit feet in -25°C, freezing with 80% to 95% ethanol, and freezing rabbit ears with solid carbon dioxide...

2020-08-10
How to prepare an electric burn animal model?

How to prepare an electric burn animal model?

Human body electric burns are mainly high-voltage electric burns. High-voltage electrical injuries are not only different from ordinary burns in the nature and scope of local wounds, but also increase the complexity of condition determination and loc...

2020-08-10
Small pig scald model-【animal modeling】

Small pig scald model-【animal modeling】

Feeding methods Before the experiment, the miniature pigs were fasted for 12 hours. After anesthesia, 0.7 g/kg body weight of 50 g/L thiopental sodium was injected intraperitoneally in a 40 cm×25 cm area to shave the hair...

2020-08-10