【Animal modeling】-Effect of deoxycholic acid on the growth of ileal organoids in C57BL/6 mice

To investigate the changes in the structure of intestinal flora in quail with hyperuricemia, and to provide reference for the study of the pathological mechanism of hyperuricemia...

2024-01-10

【Animal modeling】-Effect of astragaloside Ⅱ on IL-21/STAT3 pathway and airway inflammation in juvenile asthmatic rats

To investigate the effect of astragaloside Ⅱ on the interleukin-21 ( IL-21 ) / signal transducer and activator of transcription 3 ( STAT3 ) pathway and airway inflammation in juvenile asthmatic rats...

2024-01-10

【Animal modeling】-Effect of tacrolimus on the expression of rat liver tissue protein phosphatase 2A and P-AKT

By observing the effects of tacrolimus on blood glucose, insulin levels, hepatic tissue protein phosphatase 2A and phosphorylated AKT expression in rats, to further explore the mechanism of tacrolimus-induced blood glucose elevation...

2024-01-10

【Animal modeling】-Effect of modified Wuzhuyu decoction on hypertension and vascular endothelial function in rats induced by high sugar, high fat and alcohol consumption

To investigate the effect of modified Wuzhuyu Decoction on blood pressure and vascular endothelial function in hypertensive model rats induced by high-sugar and high-fat diet and drinking...

2024-01-10

【Animal modeling 】- Chronic liver injury model induced by sucrose and alcohol

Rats, weighing 200-250g, regardless of gender; Medications: sucrose, alcohol...

2024-01-09

【Animal modeling 】- Animal model of trauma induced blood stasis syndrome

Adult rabbits were fixed on a rabbit platform, and a lever pressure device was used to apply 7.5kg of pressure on the inner thigh muscle of the right hind limb for 1.5 hours. The changes in muscle temperature, leg diameter, hind limb blood flow, conj...

2024-01-09

[Animal Modeling] - Animal Model of Heat Toxicity and Blood Stasis Syndrome

Adult rabbits, with heart blood taken before and after the experiment to determine hemorheological and coagulation indicators...

2024-01-09

[Animal modeling] - Establishment of orthotopic liver cancer transplantation model in nude mice

To establish an orthotopic liver cancer transplantation model in BALB/c nude mice...

2024-01-09

[Animal modeling] - Chronic liver injury model induced by carbonyl iron and alcohol

Rats, weighing 200-250g, regardless of gender; Medication: carbonyl iron, Lieber Decarli liquid feed...

2024-01-09

[Animal modeling] - alcohol induced chronic liver injury model in pigs

miniature pigs, regardless of gender; Medication: Feed containing sufficient nutrients and alcohol (alcohol accounts for 40% of total calories)...

2024-01-09

[Animal Modeling] - Animal Model of Qi Deficiency and Blood Stasis Syndrome

Adult rats were placed in a water tank with a water temperature of (42 ± 1) ℃ and swam once a day until they naturally sank and were unable to float. They were anesthetized for 10 consecutive days, and their hearts were taken for blood collection and...

2024-01-09

[Animal modeling] - alcohol induced chronic liver injury model in baboons

baboons, regardless of gender; Medication: Alcoholic liquid feed containing sufficient nutrients (alcohol accounts for 50% of total calories)...

2024-01-09

[Animal Modeling] - Animal Model of Qi Stagnation and Blood Stasis Syndrome

In adult rabbits, the acupuncture and moxibustion needles were inserted subcutaneously into both ears, connected to the electroacupuncture instrument with wires, stimulated with intermittent waves every 10 minutes for 0.5 min each time, causing sudde...

2024-01-09

【Animal modeling 】- A chronic liver injury model induced by alcohol containing sufficient nutrients

Wistar rats, weighing 250-300g, regardless of gender; Medication: Alcoholic liquid feed containing sufficient nutrients (alcohol accounts for 47% of total calories); Instruments: gastric tube, micro infusion pump...

2024-01-09

【Animal Modeling】 - Animal Model of Blood Type and Blood Stasis Syndrome in Li Jing

Adult rabbits, take 10ml/kg of blood from the heart, inject 20ml into a small beaker, and let it settle. 20 minutes later, the animal underwent a laparotomy under local anesthesia, with the blood clot placed under the colon and sutured to close the a...

2024-01-09

[Animal modeling] - Comparative study of spontaneous and induced type 2 diabetes mouse models

To compare the differences in glucose metabolism, insulin resistance and inflammatory reaction between spontaneous and induced type 2 diabetes mouse models...

2024-01-08