【Disease animal model】-induced atopic dermatitis animal model

The small molecule hapten combines with proteins in the body to form a complete antigen, which is absorbed by Langerhans cells. The corresponding antigen is presented to T cells and activated, and contact dermatitis occurs again...

2023-11-13

[Animal modeling] - Preparation of alcoholic cardiomyopathy mouse model by liquid feed

To establish a mouse model of alcoholic cardiomyopathy (ALCM) with liquid feed, and provide a good animal model for the study of the mechanism of ALCM...

2023-11-13

【Animal modeling】-Effect of Bcl-2 inhibitor on astragalus injection on reducing the apoptosis of hippocampal neurons in rats with hypoxia and hypoglycemia/reoxygenation and reglycemia

To investigate the effect of astragalus injection (AI) on the apoptosis of hippocampal neurons in hypoxia-hypoglycemia/reoxygenation and reglycemia (H/R) rats under the action of Bcl-2 inhibitor (TW-37)...

2023-11-13

[Animal modeling] - Establishment of long-term depression mouse model and observation of behavioral and neuropathological characteristics

To construct a new model of long-term depression in mice, and compare the advantages and disadvantages of this model with common depression models...

2023-11-13

[Animal modeling] - Analysis on the preparation and comparison of animal models of facial paralysis

To search the relevant literature on different models of facial paralysis, analyze the advantages and disadvantages of various model preparation methods, and explore the preparation methods suitable for different types of models, so as to provide exp...

2023-11-13

【Animal Modeling】-Mini-pig Ⅱ degree root bifurcation defect model

Experimental method 4 Chinese piglets are 13 months old, male, weighing 28.5-31.5k. After normal anesthesia, the miniature pig is fixed on the animal\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\\'s operating table, sterilized and cov...

2023-11-13

【Animal Modeling】- Establishment of a mouse model of lung metastasis and postoperative recurrence after bone marrow injection

To establish a model of lung metastasis and postoperative recurrence by bone marrow injection, to reveal the superiority and feasibility of the model by bone marrow injection, and to provide a new research basis for the study of lung metastasis of ma...

2023-11-13

[Animal modeling ]- Ebola virus non human primate model

Many non-human primates have been used in the study of Ebola animal models, including African green monkeys, baboons, rhesus monkeys, and crab eating monkeys...

2023-11-10

[Animal modeling] - Atherosclerosis model induced by acrylamide hydrochloride

Rabbit, regardless of gender; Medication: 1% acrylamide hydrochloride...

2023-11-10

[Animal modeling] - establishment of carotid atherosclerosis model in rabbits by balloon injury and high-fat diet

Male Chinese large eared white rabbit, weighing 2.25-2.75kg; Medications: Granular feed containing 1.0% cholesterol and 6% lard, anesthetics, antibiotics; Instrument: Balloon catheter (2.5mm balloon)...

2023-11-10

[Animal Modeling ]- Double Kidney and Double Clamp Renal Vascular Hypertension Model

Male SD rats, weighing 80-120g; Drug: pentobarbital; Instrument: Made of a \"Q\" circular silver clip with a diameter of 0.5mm silver wire and an inner diameter of 0.3mm...

2023-11-10

[Animal Modeling] - Modified Rat Model of Acute Necrotizing Pancreatitis

SD rats, weighing 250-350g, regardless of gender; Medications: Sodium taurocholate, bioprotein gel, ketamine...

2023-11-10

【Animal Modeling】 - Hypertensive Kidney Yin Deficiency Animal Model

Adult rats were subjected to removal of one kidney and ligation of 2/3 of the other renal artery. The tail artery blood pressure of the rats was measured 2 weeks after surgery, and those with a systolic blood pressure greater than 140mmHg (18.6kPa) w...

2023-11-09

[Animal modeling] - lean diabetes mice

　　Lean diabetes mice originated from ICR mice. There is a significant difference in the time when diabetes occurs between male and female mice. The incidence of disease in female rats was more than 90 days old, and the incidence of incidence rate in ...

2023-11-07

[Animal modeling] - Animal model of alveolar hydatid disease

① Anesthetize animals infected with echinococcus multilocularis with ether, open the abdominal cavity under sterile conditions, remove the echinococcus multilocularis cyst, rinse with physiological saline, cut the cyst wall, filter 40 mesh, and prepa...

2023-11-07

[Animal modeling ]- histamine induced allergic conjunctivitis model in rats

Histamine is an important mediator for rapid allergic reactions and local inflammatory reactions. It can increase the permeability of capillaries, dilate blood vessels, and allow plasma proteins and fluids to enter tissue gaps, causing local edema, t...

2023-11-07