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【Animal Modeling】-Comparison of Depression and Anxiety-like Behaviors in Mice of Different Ages

【Animal Modeling】-Comparison of Depression and Anxiety-like Behaviors in Mice of Different Ages

To observe and compare the depression and anxiety-like behaviors of experimental mice of different ages...

2023-04-18
【Animal Modeling】-Construction of Bpi Gene Knockout Mice Using CRISPR/Cas9 Technology

【Animal Modeling】-Construction of Bpi Gene Knockout Mice Using CRISPR/Cas9 Technology

To use CRISPR/Cas9 gene editing technology to efficiently construct Bpi gene knockout mouse model, and to continue to breed, identify and build stable genetic Bpi gene knockout mouse strains...

2023-04-18
【Animal modeling】-Protective effect of trigonelline on testicular injury induced by heat stress in mice

【Animal modeling】-Protective effect of trigonelline on testicular injury induced by heat stress in mice

To study the protective effect of trigonelline on heat stress-induced testicular injury in mice...

2023-04-14
【Animal Modeling】-Comparison of Transparency of Six Optical Transparency Methods in Rat Brain Tissue Blocks

【Animal Modeling】-Comparison of Transparency of Six Optical Transparency Methods in Rat Brain Tissue Blocks

To compare the transparent effects of six optical clearing methods on rat brain tissue blocks...

2023-04-13
To observe the effect of the preparation \\\"Fujiu Tie Gao\\\" of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine on serum interleukin-4, interferon γ, related

To observe the effect of the preparation \\\"Fujiu Tie Gao\\\" of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine on serum interleukin-4, interferon γ, related

To observe the effect of the preparation \\\"Fujiu Tie Gao\\\" of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine on serum interleukin-4, interferon γ, related immunoglobulin E cytokines, nerve growth factor a...

2023-04-13
【Animal Modeling】-Based on LC-MS-based Metabolomics Study of Coronary Heart Disease-derived Microbiota in Mice

【Animal Modeling】-Based on LC-MS-based Metabolomics Study of Coronary Heart Disease-derived Microbiota in Mice

To study the characteristic metabolites of mice with coronary heart disease-derived microbiota using non-targeted metabolomics technology based on liquid chromatography-mass spectrometry...

2023-04-13
【Animal modeling】-Establishment of standard biological indicators of SD rats in GLP barrier environment animal laboratory

【Animal modeling】-Establishment of standard biological indicators of SD rats in GLP barrier environment animal laboratory

To establish the biological indicators of normal SD rats in the long-term toxicity test in the barrier environment animal laboratory of the Chinese Medicine Safety Evaluation Center (CLP), and to provide reference indicators for future researchers...

2023-04-13
【Animal Modeling】-Effect and mechanism of fine particulate matter PM2.5 on atherosclerosis in ApoE knockout mice

【Animal Modeling】-Effect and mechanism of fine particulate matter PM2.5 on atherosclerosis in ApoE knockout mice

The purpose of this experiment was to investigate the effect and mechanism of fine particulate matter PM2.5 on ApoE knockout (Apoe-/-) mice (atherosclerosis model mice)...

2023-04-13
【Animal modeling】-Hydroxyethyl starch 40 sodium chloride injection allergic experimental study

【Animal modeling】-Hydroxyethyl starch 40 sodium chloride injection allergic experimental study

To evaluate the allergic safety of hydroxyethyl starch 40 sodium chloride injection...

2023-04-13
【Animal Modeling】-Effect of chronic PM2.5 exposure on lung inflammation and NLRP3 inflammasome activity in C57BL/6J mice

【Animal Modeling】-Effect of chronic PM2.5 exposure on lung inflammation and NLRP3 inflammasome activity in C57BL/6J mice

To study the effects of chronic PM2.5 exposure on pneumonia and NLRP3 inflammasome activity in mice, and to provide new targets for the prevention and treatment of PM2.5-induced lung injury...

2023-04-12
【Animal Modeling】- Camouflage technology inspired by skin cells of cephalopods

【Animal Modeling】- Camouflage technology inspired by skin cells of cephalopods

A study found that combining a temperature-sensitive dye on a thin, flexible electrical substrate with a distributed light sensor could lead to systems that have the ability to automatically adapt to match the color of their surroundings, as a way fr...

2023-04-12
【Animal Modeling】-Changes of telemetry EEG activity in the sublimbic region of morphine-dependent rats during drug-seeking extinction

【Animal Modeling】-Changes of telemetry EEG activity in the sublimbic region of morphine-dependent rats during drug-seeking extinction

To discuss the effects of telemetry EEG activity in the sublimbic region on drug-seeking behavior in morphine-dependent rats during drug-seeking decline and its mechanism...

2023-04-12
【Animal Modeling】-Ginkgo biloba extract has been shown to promote ischemic brain injury repair and regeneration in mouse experiments

【Animal Modeling】-Ginkgo biloba extract has been shown to promote ischemic brain injury repair and regeneration in mouse experiments

Researchers from the University of Toledo found that Ginkgo biloba extract EGB 761 can promote ischemic brain damage repair and regeneration...

2023-04-11
【Animal modeling】-The effect and mechanism of rapamycin on myocardial injury after renal ischemia-reperfusion in rats

【Animal modeling】-The effect and mechanism of rapamycin on myocardial injury after renal ischemia-reperfusion in rats

To investigate the effect of rapamycin on the heart injury of distant organs after renal ischemia-reperfusion in rats...

2023-04-11
National Natural Hotspot: Super detailed! This article will help you easily understand DNA methylation [practical dry goods]

National Natural Hotspot: Super detailed! This article will help you easily understand DNA methylation [practical dry goods]

Today\\\'s short edition will introduce the natural hot spot of a country: DNA methylation. DNA methylation research has always been a multi hotspot of top journals, funding, clinical research, drug research, development and marketing...

2023-04-11
[Animal Modeling] - Su Jiacan/Chen Xiao/Jing Yingying Team Reveals Key Links in the Development of Osteoarthritis

[Animal Modeling] - Su Jiacan/Chen Xiao/Jing Yingying Team Reveals Key Links in the Development of Osteoarthritis

Osteoarthritis is a total joint disease characterized by degeneration of articular cartilage, abnormal remodeling of subchondral bone, osteophyte formation, and joint inflammation. The prevalence of knee osteoarthritis in people aged 65 and above is...

2023-04-10