[Animal modeling] - Using orthogonal test to optimize the establishment of rat\'s conditioned fear memory model

To optimize the best experimental parameters for establishing the rat model of conditioned fear memory by using orthogonal test, and to find the best experimental conditions...

2022-11-03

[Animal modeling] - Construction of bioluminescence human liver cancer in situ model in nude mice

To construct a tumor bearing nude mouse model of human hepatoma cell line in situ by using human hepatoma cell line (HCCLM3 Luc) stably expressing luciferase reporter gene...

2022-11-03

[Animal modeling] - Study on rat model of atherosclerosis (Qi stagnation and blood stasis syndrome) combined with disease and syndrome

To construct a rat model of atherosclerosis combining disease and syndrome, and provide an evaluation tool for the pharmacodynamic study of corresponding Chinese herbal compound...

2022-11-03

[Animal modeling] - Establishment of mastitis model in mice infected with Staphylococcus aureus and changes of IL-2 and IL-4

To investigate the changes of inflammatory factors interleukin 2 (IL-2) and interleukin 4 (IL-4) in the pathogenesis of mastitis in mice...

2022-11-03

[Animal modeling] - Evaluation of motor perception behavior of non-human primate unilateral brain injury model

To evaluate the functional changes of brain regions related to brain perception and motor behavior response, which is an important strategy for clinical transformation research of major brain diseases based on non-human primates in brain science rese...

2022-11-03

[Animal modeling] - Comparison of two compound models of hepatitis B liver fibrosis in mice

To compare the virological and biochemical pathological characteristics of C57BL/6N Tg (1.28HBV)/Vst hepatitis B virus transgenic mice and rAAV8-1.3HBV adeno-associated virus transfected mice combined with CCl4 intraperitoneal injection to induce hep...

2022-11-03

[Animal modeling]- β- Establishment of animal model of dissecting aneurysm induced by aminopropionitrile

Explore β- The effect of aminopropionitrile on the wall of rat great arteries and the characteristics of human dissecting aneurysms were compared with a view to further exploring the animal model of dissecting aneurysms that conforms to the character...

2022-11-03

[Animal modeling] - Expression changes of PKA and endothelial chemokine-5 in prefrontal cortex of rats with schizophrenia

To establish a rat model of schizophrenia, observe the pathological damage and the expression of PKA and endothelial chemoattractant factor-5 in prefrontal cortex, clarify the mechanism of nerve injury, and provide reference for clinical treatment...

2022-11-03

[Animal modeling] - Establishment and significance of electrophysiological detection model during dorsal penile neurectomy in beagle dogs

To investigate the detection method of somatosensory evoked potential (SEP) in beagle penis under general anesthesia and the changes of SEP during dorsal penile nerve resection, so as to provide reference for further research...

2022-11-02

[Animal modeling] - The role of small animal ultrasound in the diagnosis of mouse thoracic aortic aneurysm/dissection model

To explore a simple and rapid method to evaluate the success of the establishment of the mouse model of thoracic aortic aneurysm/dissection...

2022-11-02

[Animal modeling] - Establishment and evaluation of a mouse model of human intestinal flora of coronary heart disease

To establish a mouse model of human intestinal flora of coronary heart disease by fecal bacteria transplantation and evaluate the model...

2022-11-02

[Animal modeling] - Application analysis of asthma animal model based on data mining

To analyze the modeling factors of asthma animal models, and to provide methodological reference for improving the success rate of modeling and effectively evaluating the tested drugs...

2022-11-02

[Animal modeling] - Infection of TNF by Listeria monocytogenes α Establishment and application of humanized mouse model

To evaluate TNF ⁃ α Susceptibility of host to listeria monocytogenes infection after intervention of monoclonal antibody...

2022-11-02

[Animal modeling] - Study on the regulatory effect and mechanism of silencing miRNA-16 on immune function of pulmonary tuberculosis model mice

To study the regulatory effect of silent miR-16 on immune function of pulmonary tuberculosis model mice and its mechanism...

2022-11-02

[Animal modeling] Experimental observation on evaluation points of blood glucose intervention in type 2 diabetes mouse model

To observe the changes of blood glucose in type 2 diabetes mouse model, and explore the feasibility of blood glucose 2 hours after meal as a blood glucose intervention evaluation point...

2022-11-02

[Animal modeling] - Analysis of magnetic resonance spectroscopy and ultrastructure in hippocampus of APP/PS1 double transgenic AD model mice

To observe the relationship between the changes of metabolites in the hippocampus of APP/PS1 transgenic mice and the ultrastructural pathological changes, so that the APP/PS1 transgenic mice can be better used in the experimental study of Alzheimer\'...

2022-11-02