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【Animal Modeling】-Establishment of a rat model of myocardial cell mitochondrial injury induced by bupivacaine

【Animal Modeling】-Establishment of a rat model of myocardial cell mitochondrial injury induced by bupivacaine

To observe the changes of mitochondrial morphology and reactive oxygen species generation in bupivacaine cardiomyocytes under electrical stimulation, and to explore the establishment of an ideal rat cardiomyocyte model of bupivacaine poisoning...

2022-09-14
【Animal Modeling】-Establishment of a rat model of fear and stress and analysis of its visual cognitive effect

【Animal Modeling】-Establishment of a rat model of fear and stress and analysis of its visual cognitive effect

To construct a rat model of different degrees of fear stress, and to explore the effect of fear stress on the visual cognitive ability of LE rats...

2022-09-14
【Animal modeling】-Establishment and evaluation of a rat model of visceral hypersensitivity induced by foot shock

【Animal modeling】-Establishment and evaluation of a rat model of visceral hypersensitivity induced by foot shock

To establish a rat model of visceral hypersensitivity by plantar electric shock, and to evaluate its effectiveness and advantages...

2022-09-14
【Animal modeling】-Preliminary study on the expression profile of serum cytokines in rats with collagen-induced arthritis disease/syndrome

【Animal modeling】-Preliminary study on the expression profile of serum cytokines in rats with collagen-induced arthritis disease/syndrome

To study the expression of serum cytokines in collagen-induced rheumatoid arthritis, cold-damp bi and damp-heat bi disease/syndrome model rats...

2022-09-14
【Animal Modeling】-Establishment of a nude mouse model of colon cancer liver metastasis

【Animal Modeling】-Establishment of a nude mouse model of colon cancer liver metastasis

To construct a colon cancer liver metastasis model with high metastasis rate, simple operation and reliable results for experimental research on the prevention and treatment of colon cancer metastasis...

2022-09-14
【Animal modeling】-Hpd gene modification to prepare hypertyrosinemia type III Bama minipig model

【Animal modeling】-Hpd gene modification to prepare hypertyrosinemia type III Bama minipig model

To use CRISPR/Cas9 technology to knock out 4-hydroxyphenylpyruvate oxidase in Bama minipig to create a hypertyrosinemia type III Bama minipig model...

2022-09-14
【Animal Modeling】-Establishment and Research of Rat Hyperuricemia Model

【Animal Modeling】-Establishment and Research of Rat Hyperuricemia Model

To establish a rat model of hyperuricemia, and to explore whether hyperuricemia can lead to secondary cardiovascular disease...

2022-09-13
【Animal Modeling】-Establishment and evaluation of a mouse model of endogenous infection induced by intestinal dissemination

【Animal Modeling】-Establishment and evaluation of a mouse model of endogenous infection induced by intestinal dissemination

To establish a mouse model of endogenous infection induced by intestinal dissemination, and to provide a reliable experimental model for studying the mechanism of intestinal microecology and endogenous infection...

2022-09-13
【Animal Modeling】-Bioinformatics analysis of TNF-α-induced osteoarthritis cell model based on gene chip

【Animal Modeling】-Bioinformatics analysis of TNF-α-induced osteoarthritis cell model based on gene chip

Osteoarthritis is the most common degenerative chronic joint disease, but its specific genetic mechanism is still not fully understood. The gene expression profile changes of OA cell models were detected by gene chip to provide more biological resour...

2022-09-13
【Animal modeling】-Establishment of allergic asthma model in mice aggravated by respiratory administration of antibiotics

【Animal modeling】-Establishment of allergic asthma model in mice aggravated by respiratory administration of antibiotics

The mechanism of traditional Chinese medicine to treat diseases by regulating the flora has been gradually discovered, and to explore the establishment of an asthma model of respiratory flora disorder caused by antibiotics, in order to provide a suit...

2022-09-13
【Animal modeling】-The establishment of CA16-infected tree shrew lung fibroblast model and the expression of its receptor SCARB2

【Animal modeling】-The establishment of CA16-infected tree shrew lung fibroblast model and the expression of its receptor SCARB2

To explore the feasibility of establishing an experimental model of CA16-infected tree shrew lung fibroblasts...

2022-09-13
【Animal Modeling】-Using Orthogonal Test to Optimize the Establishment of a Rat Conditioned Fear Memory Model

【Animal Modeling】-Using Orthogonal Test to Optimize the Establishment of a Rat Conditioned Fear Memory Model

To optimize the optimal experimental parameters for establishing a conditioned fear memory model in rats by using orthogonal experiments, and to find the optimal experimental conditions...

2022-09-13
【Animal Modeling】-Analysis of Mozart\'s K448 Sonata High-frequency Sound Wave on Intervention and Treatment of Depression Model in Mice

【Animal Modeling】-Analysis of Mozart\'s K448 Sonata High-frequency Sound Wave on Intervention and Treatment of Depression Model in Mice

To establish a depression model in C57BL/6 mice, and to preliminarily explore the effect of high-frequency sound waves in Mozart\'s K448 sonata on improving depressive symptoms in C57BL/6 mice...

2022-09-13
【Animal Modeling】-Construction of a Bioluminescent Human Liver Cancer Nude Mouse Model of Carcinoma In Situ

【Animal Modeling】-Construction of a Bioluminescent Human Liver Cancer Nude Mouse Model of Carcinoma In Situ

To select a human hepatoma cell line (HCCLM3-Luc) stably expressing a luciferase reporter gene, and to construct an in situ tumor-bearing nude mouse model of human hepatoma cell line...

2022-09-13
【Animal modeling】-Establishment of an inflammatory model of BALB/c mice infected with influenza A virus

【Animal modeling】-Establishment of an inflammatory model of BALB/c mice infected with influenza A virus

To analyze the pathogenicity of influenza A virus using a mouse model of inflammation...

2022-09-13
【Animal Modeling】-Comparison of Two Hepatitis B Hepatitis B Fibrosis Mouse Compound Models

【Animal Modeling】-Comparison of Two Hepatitis B Hepatitis B Fibrosis Mouse Compound Models

To use C57BL/6N-Tg(1.28HBV)/Vst hepatitis B virus transgenic mice and rAAV8-1.3HBV adeno-associated virus-transfected mice combined with CCl4 intraperitoneal injection to induce hepatitis B fibrosis mouse model, and compare the two mice Virological a...

2022-09-13