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【Animal Modeling】- Overexpression of LAMP2A in the substantia nigra improves motor function in a rhesus monkey model of Parkinson\'s disease

【Animal Modeling】- Overexpression of LAMP2A in the substantia nigra improves motor function in a rhesus monkey model of Parkinson\'s disease

To observe the effect of overexpression of lysosome-associated membrane protein 2A in substantia nigra on chaperone-mediated autophagy on motor behavior in a rhesus monkey model of Parkinson\'s disease...

2022-08-04
【Animal Modeling】-Construction and Evaluation of Humanized Mouse Model of Pancreatic Cancer Immune System

【Animal Modeling】-Construction and Evaluation of Humanized Mouse Model of Pancreatic Cancer Immune System

To construct and evaluate a humanized mouse model of pancreatic cancer immune system, in order to provide an ideal preclinical model for the immunotherapy of pancreatic cancer...

2022-08-04
【Animal Modeling】-3D Reconstruction and Vascular 3D Printing Model of Miniature Pig Lungs

【Animal Modeling】-3D Reconstruction and Vascular 3D Printing Model of Miniature Pig Lungs

To discuss the establishment of 3D reconstruction model of minipig lungs and the application of 3D printing model...

2022-08-04
【Animal modeling】-Arachidonic acid-induced establishment of diffuse cerebral thrombosis model in rats

【Animal modeling】-Arachidonic acid-induced establishment of diffuse cerebral thrombosis model in rats

Objective To establish and optimize the rat model of diffuse cerebral thrombosis induced by arachidonic acid...

2022-08-04
【Animal Modeling】-Preparation of a mouse model of diarrhea-type irritable bowel syndrome induced by acetic acid combined with restraint stress

【Animal Modeling】-Preparation of a mouse model of diarrhea-type irritable bowel syndrome induced by acetic acid combined with restraint stress

A mouse model of diarrhea-predominant irritable bowel syndrome was established by rectal infusion of 3% acetic acid (AA) combined with restraint stress, and the feasibility of the model was evaluated...

2022-08-04
【Animal Modeling】-3D Reconstruction and Vascular 3D Printing Model of Miniature Pig Lungs

【Animal Modeling】-3D Reconstruction and Vascular 3D Printing Model of Miniature Pig Lungs

To discuss the establishment of 3D reconstruction model of minipig lungs and the application of 3D printing model...

2022-07-29
PNAS: Types of beta amyloid and patterns of Alzheimer\'s disease pathogenesis

PNAS: Types of beta amyloid and patterns of Alzheimer\'s disease pathogenesis

Inoculation of mice with brain homogenates from sporadic Alzheimer\'s disease patients elicited cerebral amyloid deposition in recipients, suggesting that the amyloid beta (Aβ) peptide may self-proliferate as a prion...

2022-07-29
【Animal Modeling】- Camouflage technology inspired by skin cells of cephalopods

【Animal Modeling】- Camouflage technology inspired by skin cells of cephalopods

A study found that combining a temperature-sensitive dye on a thin, flexible electrical substrate with a distributed light sensor could lead to systems that have the ability to automatically adapt to match the color of their surroundings, as a way fr...

2022-07-28
【Animal modeling】-Defensive effects of curcumin and tea polyphenols on UVB-induced acute light damage in hairless rats at different times

【Animal modeling】-Defensive effects of curcumin and tea polyphenols on UVB-induced acute light damage in hairless rats at different times

To investigate the protective effects of curcumin and tea polyphenols on UVB-induced acute light damage in hairless rats at different times...

2022-07-28
【Animal modeling】-Construction and research of eukaryotic expression vector of full-length and mature IL-37b

【Animal modeling】-Construction and research of eukaryotic expression vector of full-length and mature IL-37b

To construct the eukaryotic expression vector pEGFP N1/IL-37b of full-length and mature IL-37b, and to detect the expression of both in RAW 264.7 cells....

2022-07-27
【Animal modeling】-The correlation analysis of plasma cytokines and disease indications in rhesus monkeys infected with SIVmac239 treated with HAART

【Animal modeling】-The correlation analysis of plasma cytokines and disease indications in rhesus monkeys infected with SIVmac239 treated with HAART

To detect the plasma cytokine concentrations of SIVmac239 (simian immunodeficiency virus)-infected rhesus monkeys and analyze their correlation with disease characteristics...

2022-07-27
【Animal modeling】-Analysis of biological parameters and cardiac physiological function in mice overexpressing Slit2 gene

【Animal modeling】-Analysis of biological parameters and cardiac physiological function in mice overexpressing Slit2 gene

To measure and evaluate the basic biological parameters, cardiac ultrasound morphology and function, and transcriptome sequencing of human Slit2 gene overexpressing mice (Slit2-Tg mice), so as to provide reference for the application of this mouse in...

2022-07-27
【Animal Modeling】-Dynamic changes of blood physiological and biochemical indexes during the cultivation of diabetic inbred strains of gerbils

【Animal Modeling】-Dynamic changes of blood physiological and biochemical indexes during the cultivation of diabetic inbred strains of gerbils

To investigate the dynamic changes and regularities of blood physiological and biochemical indexes during the cultivation of diabetic inbred strains of gerbils...

2022-07-27
【Animal modeling】-Changes and significance of oxidative stress and cytokines in the formation of non-alcoholic fatty liver disease in gerbils

【Animal modeling】-Changes and significance of oxidative stress and cytokines in the formation of non-alcoholic fatty liver disease in gerbils

To study the dynamic changes and significance of oxidative stress and cytokines in the formation of nonalcoholic fatty liver disease in gerbils...

2022-07-26
【Animal Modeling】-Comparison of two different reagents for the four detection results of hemagglutination in SD rats

【Animal Modeling】-Comparison of two different reagents for the four detection results of hemagglutination in SD rats

To compare the four test results of hemagglutination reagents from two different manufacturers, imported and domestic, on experimental animals SD rats and humans, and to observe whether there is any difference between them...

2022-07-26
【Animal Modeling】-Experiment on the Effect of Curcumin on the Survival Rate of Rats in Desert Dry-Hot Environment

【Animal Modeling】-Experiment on the Effect of Curcumin on the Survival Rate of Rats in Desert Dry-Hot Environment

To investigate the effect of curcumin on the survival rate of rats in the desert hot and dry environment...

2022-07-26