【Animal modeling】-Dynamic monitoring of virus antibodies during the establishment of SPF population in cynomolgus monkeys

To investigate the proportion of positive and suspicious antibodies against four cynomolgus monkeys BV, SRV, SIV and STLV-1 introduced from Laos, and to monitor the dynamic changes of the four viruses during the establishment of the SPF population, s...

2022-06-14

【Animal Modeling】-Effects of cold acclimation on adaptive thermogenesis in brown adipose tissue of Chinese shrew

To investigate the effect of ambient temperature on body weight, brown adipose tissue (BAT) thermogenesis and uncoupling protein 1 content of Chinese tree shrew, and to provide a theoretical basis for establishing a tree shrew obesity model...

2022-06-14

【Animal Modeling】-Distribution of different doses of propofol in different brain regions of neonatal rats

To investigate the ideal dose of propofol for intraperitoneal anesthesia in neonatal rats and the distribution of propofol in different brain regions of neonatal rats...

2022-06-14

【Animal modeling】-In vitro differentiation of mouse umbilical cord mesenchymal stem cells

To isolate and expand mouse umbilical cord mesenchymal stem cells to investigate whether they can be induced into cartilage, adipose and osteoblasts...

2022-06-14

【Animal modeling】-Analysis of basic data of blood pressure and body temperature in rats with congenital cataract

In order to improve the background data of congenital cataract rats, the blood pressure, body weight and body temperature of the rats were measured, and the correlation was analyzed...

2022-06-14

【Animal Modeling】-Analyze the genetic characteristics of 7 strains of commonly used inbred mouse core groups in Shanghai using multiple fluorescent STR technology

To compare the genetic characteristics of 7 strains of commonly used inbred mouse core groups in Shanghai area...

2022-06-14

【Animal modeling】-Isolation, culture and identification of hepatic stellate cells in gerbils

To explore a stable and economical method for the isolation and culture of hepatic stellate cells in gerbils, and to provide technical support for the in-depth study of the cellular mechanism of hepatic fibrosis in gerbils...

2022-06-14

【Animal Modeling】-Construction and Identification of Targeted Regulation of CNN3 Gene Expression Vector in Rat Hippocampus

To establish a technology that can regulate the expression of CNN3 gene in local brain regions of rats, and lay a foundation for further research on the involvement of CNN3 gene in the pathophysiological process of the brain...

2022-06-14

【Animal Modeling】-Tail-suspended mice infected with space-mutated Escherichia coli have enhanced inflammatory response

To observe the changes of inflammatory response after space-mutated Escherichia coli infection of tail-suspended mice simulated weightlessness...

2022-06-14

【Animal modeling】-Preliminary exploration of hepatic shear wave velocity in mice with hepatic fibrosis based on acoustic radiation force pulse elastography

To explore the characteristics and significance of intrahepatic shear wave velocity changes in mice with carbon tetrachloride (CCl4)-induced hepatic fibrosis using acoustic radiation force pulse elastography...

2022-06-13

【Animal Modeling】-Effect of two-color coreopsis alcohol extract on intestinal flora of type 2 diabetic mice

To explore the possible link between the alcoholic extract of coreopsis bicolor, intestinal flora and type 2 diabetes mellitus...

2022-06-13

【Animal Modeling】-Comparison of Metabolic Syndrome-related Indicators of Two Miniature Pigs

Bama miniature pigs and Tibetan miniature pigs were selected, and their body weight, body size, and metabolic syndrome-related indicators-blood lipids, blood glucose, and free radical levels were compared and analyzed among different species and gend...

2022-06-13

【Animal modeling】-Expression and purification of Asprosin and its effect on mouse cardiac function in vivo

To express and purify asprosin protein in prokaryotic cells of Escherichia coli, and to study its effect on the improvement of cardiac function...

2022-06-13

【Animal Model】-Protective effect of liensinine on LPS-induced acute lung injury in mice

To investigate the effect of liensinine on lipopolysaccharide-induced acute lung injury (ALI) in mice...

2022-06-13

【Animal modeling】-Bama pig NK cell phenotype identification and establishment of pig CIK cell induction method

To obtain the data of the phenotype and proportion of NK cells in the peripheral blood lymphocytes of Bama pigs, and to establish a method for inducing and culturing high-efficiency porcine CIK (cytokine-induced killer) cells in vitro...

2022-06-13

【Animal modeling】-Pathological changes of amyloidosis and cerebrovascular disease in Alzheimer\\

To investigate the pathological changes of brain tissue of amyloidosis cerebrovascular lesions on the basis of establishing an experimental rat model of Alzheimer\\\'s disease...

2022-06-13