【Animal Modeling】-Application of L-Arginine in the Propagation of Drosophila in the Laboratory

The purpose of the experiment was to study the effect of adding L-arginine to corn agar medium on the pupation time, eclosion time, eclosion rate and male-female ratio of Drosophila melanogaster...

2022-05-11

【Animal modeling】-D-galactose increases the expression of IL-18 in the gut of tree shrew and the intestinal flora imbalance

To analyze the expression of IL-18 in the intestinal tissue of tree shrew and the changes of intestinal flora under the action of D-galactose...

2022-05-10

【Animal modeling】-The killing effect of PBLC of guinea pigs with different FMDV susceptibility on simulated FMDV-infected cells

To investigate the genetic and immunological mechanisms of guinea pigs resistance to foot-and-mouth disease virus (FMDV). To elucidate the feasibility of FMDV pseudovirus-infected cells for studying FMDV pathogenesis...

2022-05-10

【Animal Modeling】-Intrahepatic survival and hepatic differentiation of hUCMSCs injected into rat embryos

To observe the survival and differentiation of human umbilical cord mesenchymal stem cells labeled with green fluorescent protein in SD rat liver during embryonic stage, and to explore the feasibility of establishing human-rat chimeric liver during e...

2022-05-10

【Animal Modeling】-Programmed freezing of hatched blastocysts and their dormant embryos in mice-Differential expression of Mgst1 gene before and after thawing

To analyze the role of Mgst1 gene in programmed freezing of mouse embryos by comparing the relative expression of Mgst1 gene and the differential expression distribution of Mgst1 protein before and after programmed freezing and thawing of hatched bla...

2022-05-10

【Animal modeling】-Establishment and validation of electroporation transfection conditions for mouse macrophage RAW264.7 cells

To screen and verify the conditions for electroporation of TRIB3 overexpression plasmid and TRIB3 siRNA in RAW264.7 cells, and to establish the optimal electroporation transfection scheme for RAW264.7 cells...

2022-05-10

【Animal modeling】-α-synuclein A53T mutation impairs cognitive function in mice

To explore the changes of cognitive function, motor function, anxiety-like behavior and pathological changes in α-synuclein A53T transgenic mice...

2022-05-10

【Animal modeling】-The correlation analysis of plasma cytokines and disease indications in rhesus monkeys infected with SIVmac239 treated with HAART

To detect the plasma cytokine concentrations of SIVmac239 (simian immunodeficiency virus)-infected rhesus monkeys and analyze their correlation with disease characteristics...

2022-05-10

【Animal modeling】-Effect of perfluorooctane sulfonate on rat embryonic development and placental IGF-1 expression

To investigate the effects of different doses of perfluorooctane sulfonate exposure on embryonic development and placental insulin-like growth factor-1 expression in rats...

2022-05-10

【Animal Modeling】-Mice Mycoplasma Pneumoniae Model

Replication method The Mycoplasma pneumoniae strain (ATCC29342) was cultured in SP-4 liquid medium at 37°C for 72 hours...

2022-05-10

【Animal Modeling】-Effect of Western Diet on Apolipoprotein E Knockout Mice

To study the effect of western diet and standard diet on hematology and pathology of apolipoprotein E knockout mice (ApoE-/-)...

2022-05-10

【Animal Modeling】-TALEN Construction of Fndc5 Gene Knockout Mice and Preliminary Analysis

To provide an animal model for subsequent research by constructing Fndc5 knockout mice...

2022-05-10

【Animal Modeling】-A weekly subcutaneous injection of rhPTH(1-34) promotes fracture healing in rats

To observe the effect of weekly subcutaneous injection of parathyroid hormone rhPTH (1-34) on fracture healing in rats...

2022-05-10

【Animal Modeling】-Pathological Study of Spontaneous Lesion in SD Rats of Different Ages, Genders and Environments

To observe the incidence of spontaneous lesions in SD rats of different environments, ages and genders, and to provide background data for pathological evaluation of drug safety research...

2022-05-09

【Animal modeling】-Stability analysis of peptidase-3 samples in experimental mouse kidney homogenate

To analyze the stability of peptidase-3 samples, understand the storage conditions and transportation conditions of the samples, and then take appropriate measures to ensure that the quality of proficiency testing samples always meets the requirement...

2022-05-09

【Animal Modeling】-Effects of Different Mouse Hepatitis Viruses on the Detection of Serum Antibodies by ELISA

To establish a mouse hepatitis virus serum antibody ELISA method for daily monitoring of MHV in this area, so as to timely judge the infection status of SPF mice...

2022-05-09