【Animal modeling】-Micro-CT observation of the effect of recombinant human parathyroid hormone on fracture healing in 2-month-old male rats

To investigate the effect of recombinant human parathyroid hormone (rhPTH) on fracture healing in 2-month-old male rats using Micro-CT...

2022-03-30

【Animal Modeling】-Comparison of Ulcer Wound Healing in Two Type 2 Diabetic Mice

To compare the healing characteristics of ulcer wounds in C57BL/6J-db/db and STZ-induced C57BL/6J mice with type 2 diabetes mellitus commonly used, and to conduct relevant animal experiments for the application of a stable diabetic mouse ulcer model ...

2022-03-30

【Animal modeling】-Effect of rhubarb root extract on the morphology of tissues and organs in mice with experimental psoriasis

To investigate the effect of rhubarb root extract on the morphology of tissues and organs in experimental psoriasis model mice...

2022-03-30

【Animal modeling】-Flow cytometry analysis of the phenotypic characteristics of PMA-induced THP-1 differentiation into macrophages

To clarify the differentiation of macrophages derived from THP-1 cells induced by PMA alone by flow cytometry...

2022-03-30

【Animal Modeling】-Effects of Vanadium Exposure on Inflammatory Response and Migration of Rat Microglia

To observe the effects of sodium metavanadate (NaVO3·2H2O) exposure on the inflammatory response and migration of microglia, and to explore the related mechanism of vanadium neurotoxicity...

2022-03-30

【Animal modeling】-The synergistic and detoxifying effect of pine pollen assisted by paclitaxel combined with platinum-based chemotherapy

To study whether pine pollen has attenuating and synergistic effects on paclitaxel combined with platinum-based chemotherapy...

2022-03-30

【Animal Modeling】-Effects of intermedia and adrenomedullin on cerebral microcirculation in rats with focal cerebral ischemia

To investigate the effects of intermedin and adrenomedullin on cerebral microcirculation in rats with focal cerebral ischemia...

2022-03-29

【Animal Modeling】-Cysteinyl leukotriene receptor antagonist attenuates global cerebral ischemia-reperfusion injury in gerbils by down-regulating autophagy

To investigate the protective effect and mechanism of cysteinyl leukotriene receptor antagonists (prolukast, HAMI 3379) on global cerebral ischemia-reperfusion injury in gerbils...

2022-03-29

【Animal modeling】-Comparison of dopamine content in the lateral geniculate body of guinea pigs with flash-induced myopia and form deprivation myopia

To observe the changes of dopamine (DA) content in the lateral geniculate body in guinea pig models of flicker-induced myopia and form deprivation myopia, and to conduct a comparative analysis, and to preliminarily explore the central pathogenesis of...

2022-03-29

【Animal Modeling】-Effect of high-fat diet feeding time on type 2 diabetic nephropathy rat model

To explore the effects of different high-fat diet feeding time on blood glucose, insulin resistance index (HOMA-IR) and urinary albumin excretion rate (UAER) in induced type 2 diabetic nephropathy (DN) rat model...

2022-03-29

【Animal modeling】-The effect of TRPV4 receptor on angiotensin II-induced renal damage in mice

To investigate the role of TRPV4 receptor in angiotensin II-induced renal damage by using transient receptor potential vanilloid 4 knockout (TRPV4 - / - ) mice...

2022-03-29

【Animal modeling】-Effect of botulinum toxin type A heavy chain intervention on the expression of growth-related proteins after spinal cord injury in rats

To investigate the effect of artificial recombinant botulinum toxin type A heavy chain (BoNT/A heavy chain) on the expression of local growth-related proteins in rats with spinal cord injury in vivo, and to provide a basis for elucidating the mechani...

2022-03-29

【Animal modeling】-Construction and research of eukaryotic expression vector of full-length and mature IL-37b

To construct the eukaryotic expression vector pEGFP N1/IL-37b of full-length and mature IL-37b, and to detect the expression of both in RAW 264.7 cells...

2022-03-29

【Animal Modeling】-Injury effect of high-frequency electromagnetic radiation on emotion-cognitive behavior in mice

To explore the establishment of a model of mouse emotional-cognitive behavioral damage caused by high-frequency electromagnetic radiation, and to provide an experimental basis for the study of radiation damage mechanism and protection...

2022-03-29

【Animal Modeling】-Using TaqMan probe fluorescence quantitative PCR technology to identify the genotype of Leprdb/+ mice offspring

To establish an efficient method for genotyping the offspring of Leprdb/ + mice using TaqMan probe fluorescence quantitative PCR technology...

2022-03-29

【Animal modeling】-Blocking macrophage-mediated PD1/PD-L1 pathway inhibits tuberculosis recurrence in mice

To block the macrophage-mediated PD1/PD-L1 pathway with functional PD-L1 monoclonal antibody, and to study its immune intervention effect and mechanism on the relapse of tuberculosis in mice after treatment...

2022-03-29