【Animal modeling】-Subacute inhalation toxicity study of ivermectin original drug in rats

To study the subacute inhalation toxicity of ivermectin original drug to rats and find out the maximum ineffective dose...

2022-02-09

【Animal modeling】-Effect of rapamycin on proliferation of rat aortic valve interstitial cells

To apply rapamycin to target mTOR and discuss its effect on the proliferation of rat heart valve interstitial cells...

2022-02-09

【Animal modeling】-Effect of Ghrelin on the expression of DKK-1 in the hippocampus and learning and memory function of diabetic rats

To observe the expression changes of Ghrelin on DKK-1 and WNT signaling pathways in diabetic rats, and to explore the mechanism involved in learning and memory function...

2022-02-09

【Animal modeling】-Protective effect of piperphentonamine hydrochloride on gentamicin-induced hearing loss in guinea pigs

To investigate the relationship between the expression of autophagy-related proteins beclin1 and LC3, Na+-K+-2Cl-binding transporter (NKCC1) mRNA, endothelin (ET) and cochlear gentamicin (GM) injury in guinea pig cochlea and piperphentonamine hydroch...

2022-02-09

【Animal Modeling】-Aniline-induced DNA damage in mouse hepatocytes and lymphocytes and its repair effect

To study the genotoxicity of aniline and its repair kinetics...

2022-02-09

【Animal modeling】-Effect of octachlorodibenzodioxin on gene expression profile of mouse testis tissue

To discuss the effect of octachlorodibenzodioxins on the alteration of gene expression profiles in the testis of male mice...

2022-02-09

【Animal modeling】-Protective effect of acupuncture combined with Danhong injection on cerebral ischemia-reperfusion injury in rats

To study whether acupuncture for separation of Danhong injection has protective effect on cerebral ischemia-reperfusion injury in rats...

2022-02-09

【Animal modeling】-Repair effect of embryonic stem cells on ischemia-damaged myocardium in pregnant mice

Discuss whether fetal mouse embryonic stem cells can enter the pregnant mother through the blood circulatory system and stop the repair of ischemic myocardial tissue in pregnant mice...

2022-02-09

【Animal Experiments】-Effects of Four Commonly Used Experimental Anesthetics on Cardiovascular System of Rats

To discuss the effects of different animal experimental anesthetics on the cardiovascular system of rats...

2022-02-09

【Animal modeling】-Effect of miR-126 on myocardial cell apoptosis in rats with acute myocardial infarction

To investigate the effect of miR-126 on myocardial cell apoptosis in acute myocardial infarction (AMI) rats...

2022-02-08

【Animal modeling】-Comparing the similarities and differences of oral flora between humans and commonly used experimental animals by 16S rRNA high-throughput sequencing

To use 16S rRNA high-throughput sequencing method to determine the oral flora of several commonly used experimental animals (Tibetan miniature pigs, beagle dogs, macaques, New Zealand rabbits, Wistar rats), and to compare and analyze the oral flora o...

2022-02-08

【Animal modeling】-The role of phosphokinase Czeta in the anterior cingulate cortex in emotional responses in rats with inflammatory pain induced by Freund\'s safety adjuvant

To observe the emotional response of CFA-induced inflammatory pain model rats, and to explore the relationship between the anterior cingulate cortex (ACC) phosphokinase Czeta (PKCzeta) and the emotional response of inflammatory pain rats...

2022-02-08

【Animal Modeling】-SOD activity of diabetic rats and the effect of antioxidant treatment on the antioxidant status of the body

To explore the changes of SOD activity and protein expression in main organs of diabetic rats, and to observe the effect of the antioxidant N-acetylcysteine (NAC) on the antioxidant status of the body after short-term treatment (4 weeks)....

2022-02-08

【Animal Modeling】-Changes of Blood Indexes in Long-term Toxicity Experiment of Niaotongkake Naiqi Tablets in Rats

To investigate the changes of hematological indexes in the long-term toxicity test of Niaotongkake Naiqi tablets in rats...

2022-02-08

【Animal Modeling】-The relationship between sex differences in blood pressure and sodium channels in mouse kidneys

To study blood pressure, renal urinary sodium excretion and related renal sodium channels and signaling pathways in male and female mice, and to preliminarily explore the relationship between sex differences in blood pressure and renal sodium channel...

2022-02-08

【Animal Modeling】-Multi-electrode array implantation on choroid

Retinitis pigmentosa (Rp) is a hereditary degenerative retinal disease, which causes specific loss of photoreceptors and retinal pigment epithelium (RPE), and is accompanied by severe visual impairment...

2022-02-06