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【Animal Modeling】-How to build an animal model of human intestinal flora of Alzheimer\\

【Animal Modeling】-How to build an animal model of human intestinal flora of Alzheimer\\

Fecal bacterial transplantation was used to obtain human flora-related (HFA) model mouse Alzheimer\\\'s disease through oral route, and the model was evaluated through bioinformatics, histopathology and other methods...

2022-01-31
【Animal Modeling】-What is the difference between spontaneous and induced type 2 diabetes mouse models?

【Animal Modeling】-What is the difference between spontaneous and induced type 2 diabetes mouse models?

Compare the differences in glucose metabolism, insulin resistance and inflammation between spontaneous and induced type 2 diabetic mouse models...

2022-01-31
【Animal Modeling】-Single intraosseous injection of simvastatin promotes normalization of breast cancer tumor blood vessels in mice

【Animal Modeling】-Single intraosseous injection of simvastatin promotes normalization of breast cancer tumor blood vessels in mice

To study the effect of a single intraosseous injection of simvastatin on the vascular structure and function of breast cancer tumors in mice...

2022-01-31
【Animal Modeling】-Post-traumatic stress disorder model

【Animal Modeling】-Post-traumatic stress disorder model

Establish a model of post-traumatic stress disorder through single long-term stress (SPS), and observe the effect of orphan feeding on SPS model rats...

2022-01-31
【Animal Modeling】-How to build an animal model of choroidal and retinal neovascularization?

【Animal Modeling】-How to build an animal model of choroidal and retinal neovascularization?

The development of animal models of choroidal neovascularization (CNV) and retinal neovascularization (RNV) contributes to the understanding of biology in this situation...

2022-01-31
【Animal Modeling】-How to establish a Hr gene knockout mouse model?

【Animal Modeling】-How to establish a Hr gene knockout mouse model?

Establish knockout mice and study the function of hairless gene (Hr) in detail...

2022-01-31
【Animal Modeling】-Light Thrombus Stroke Model

【Animal Modeling】-Light Thrombus Stroke Model

Stroke has a high fatality rate, disability rate and recurrence rate, which is an insurmountable disease for human beings. It is mainly divided into hemorrhagic stroke and ischemic stroke. The latter accounts for 80% of all strokes...

2022-01-31
【Animal Modeling】-Naphthoquine induces central nervous system and hepatic vascular center toxicity in Beagle dogs

【Animal Modeling】-Naphthoquine induces central nervous system and hepatic vascular center toxicity in Beagle dogs

He was approximately 14 months old at the start of the administration and weighed 7.8 to 10.1 kg. Vehicle control group (0 mg/kg/day, 1 female and 1 male), low-dose group (2 mg/kg/day, 1 female and 1 male) and medium-dose group (10 mg/kg/day, 1 femal...

2022-01-31
【Animal modeling】-Effect of low selenium diet on the expressions of CD163, CD206 and CCR7 in the liver and kidney of rats

【Animal modeling】-Effect of low selenium diet on the expressions of CD163, CD206 and CCR7 in the liver and kidney of rats

To investigate the effect of low selenium diet on liver and kidney in rats, and the role of macrophage polarization to M1 and M2 in liver and kidney fibrosis...

2022-01-28
【Animal Modeling】-Glucagon-like polypeptide-1 improves learning and memory ability in type 2 diabetic rats

【Animal Modeling】-Glucagon-like polypeptide-1 improves learning and memory ability in type 2 diabetic rats

To observe the improvement effect of diabetes treatment drug glucagon-like peptide-1 (GLP-1) on learning and memory dysfunction in diabetic rats...

2022-01-28
【Animal modeling】-Effect of hypoxic preconditioning on the formation of endometriotic lesions in rats

【Animal modeling】-Effect of hypoxic preconditioning on the formation of endometriotic lesions in rats

To understand the effect of hypoxic preconditioning on the formation of ectopic lesions in a rat model of endometriosis, so as to further clarify the molecular mechanism of the occurrence and development of EMs, so as to provide new ideas for its pre...

2022-01-28
【Animal Modeling】-Depression-like behavioral changes in male and female rats induced by restraint stress of different durations

【Animal Modeling】-Depression-like behavioral changes in male and female rats induced by restraint stress of different durations

To investigate the effects of chronic restraint stress of different restraint durations on the depression-like behavior of male and female SD rats, and to provide a basis for the selection of experimental animals\\\' gender and experimental duration ...

2022-01-28
【Animal modeling】-Effect of Bcl-2 inhibitor on astragalus injection on reducing the apoptosis of hippocampal neurons in rats with hypoxia and hypoglycemia/reoxygenation and reglycemia

【Animal modeling】-Effect of Bcl-2 inhibitor on astragalus injection on reducing the apoptosis of hippocampal neurons in rats with hypoxia and hypoglycemia/reoxygenation and reglycemia

To investigate the effect of astragalus injection (AI) on the apoptosis of hippocampal neurons in hypoxia-hypoglycemia/reoxygenation and reglycemia (H/R) rats under the action of Bcl-2 inhibitor (TW-37)...

2022-01-28
【Animal Modeling】-Study on the synergistic analgesic effect of choline and parecoxib sodium and its mechanism through mouse experiments

【Animal Modeling】-Study on the synergistic analgesic effect of choline and parecoxib sodium and its mechanism through mouse experiments

To investigate the interaction between choline and parecoxib sodium in analgesia and to conduct a preliminary study on its mechanism...

2022-01-28
【Animal modeling】-Experimental study on the differentiation of bone marrow mesenchymal stem cells into cardiomyocyte-like cells induced by Jiawei Danshen Decoction in vitro

【Animal modeling】-Experimental study on the differentiation of bone marrow mesenchymal stem cells into cardiomyocyte-like cells induced by Jiawei Danshen Decoction in vitro

Experimental study on the differentiation of bone marrow mesenchymal stem cells into cardiomyocyte-like cells induced by modified Danshen decoction in vitro...

2022-01-28
【Animal Modeling】-Effects of benzene pollution on liver and kidney function and blood nucleotide levels in rats

【Animal Modeling】-Effects of benzene pollution on liver and kidney function and blood nucleotide levels in rats

To explore the effect of benzene on liver and kidney function and blood nucleotide levels in Wistar rats...

2022-01-28