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How to prepare an animal model of hepatitis B virus infection?

How to prepare an animal model of hepatitis B virus infection?

Hepatitis B virus (HBV) is a hepatotrophic DNA virus, which is a complex DNA virus. Since the 1970s, we have identified Dane particles (HBV particles) with electron microscopes and discovered HBV particles...

2020-08-11
【Animal experiment】-Rhesus monkey infection model

【Animal experiment】-Rhesus monkey infection model

Breeding method Before the experiment, collect adult experimental rhesus monkeys, weighing 2-5 kg, and screen for HBsAg, anti-HAV and other liver function enzyme activities. After ketamine anesthesia, first collect blood samples and liver tissue biop...

2020-08-11
Genetic engineering animal model of catecholamine action system

Genetic engineering animal model of catecholamine action system

“Ércháfēn\'àn” bāokuò shènshàngxiàn sù, qù jiǎ shènshàngxiàn sù, duōbā\'àn jí qí dàixiè chǎnwù 29/5000 \"Catecholamines\" include epinephrine, norepinephrine, dopamine and their metabolites...

2020-08-11
How to prepare an orphan or separate animal model of depression?

How to prepare an orphan or separate animal model of depression?

Some primates or non-primates have characteristic manifestations such as restlessness, sleep disturbance and crying after separation of offspring...

2020-08-11
How to prepare an animal model of drug-induced depression?

How to prepare an animal model of drug-induced depression?

Drug antagonism: Reserpine can antagonize this effect. This is the earliest study to establish antidepressants, because it was found that monoamine oxidase inhibitors and tricyclic antidepressants can counteract abnormal animal behaviors caused by re...

2020-08-11
How to prepare a transgenic animal depression model?

How to prepare a transgenic animal depression model?

WKY Rats WKY (WistarKyoto) rats are sensitive to various stimuli and show behavior defects in some common behavior tests...

2020-08-11
How to prepare an animal model of depression stress?

How to prepare an animal model of depression stress?

The behavioral despair model is simple, fast and sensitive, and is usually used for rapid screening of antidepressants...

2020-08-11
How to prepare the NIH nude mouse infection animal model?

How to prepare the NIH nude mouse infection animal model?

Replication method Use 4-week-old NIH nude mice, inoculate intraperitoneally with 0.2 ml -4 power/0.5 ml virus to 100TCID10, the strain is EHFVLN-84L...

2020-08-11
How to prepare a rodent model of cerebral ischemia?

How to prepare a rodent model of cerebral ischemia?

Whole rodent models of cerebral ischemia indicate that approximately 50% of cardiac arrest survivors suffer from permanent motor or cognitive impairment...

2020-08-11
[Animal model]-HV infection model in suckling mice

[Animal model]-HV infection model in suckling mice

Replication method 48 to 72 hours after delivery, inoculate Kunming sucking mice with 0.02 ml of Hantavirus 76/118 strain (LD5010 -6.5 power/0.02 ml) adapted to sucking mice...

2020-08-11
How to prepare a rodent model of Parkinson\'s disease?

How to prepare a rodent model of Parkinson\'s disease?

Reserpine is an alkaloid that irreversibly prevents monoamine transportation in the capsule and consumes central and peripheral monoamines, thereby affecting the circulation of monoamines in intracellular vesicles. It was used to create a rat PD mode...

2020-08-11
How are rodent models of Alzheimer\'s disease prepared?

How are rodent models of Alzheimer\'s disease prepared?

The aging model of AD animals mainly occurs in the elderly, and aging is a specific risk factor for AD. With the aging of the world population, the prevalence of AD has increased significantly, and it is the fourth leading cause of death in adults, l...

2020-08-11
How to prepare a highly pathogenic avian influenza (H5N1) virus infection model?

How to prepare a highly pathogenic avian influenza (H5N1) virus infection model?

Avian influenza (AI) is an acute, high-contact and severe infection of poultry caused by influenza A virus (avian influenza virus, AIV), which can lead to poultry infection or disease syndrome...

2020-08-11
How to prepare animal models of cerebrovascular disease?

How to prepare animal models of cerebrovascular disease?

Hypertensive animals will develop spontaneous cerebral infarction, which can be divided into two categories: primary hypertension and secondary hypertension. The former is commonly used Japanese spontaneously hypertensive rats (SHR) and its prone sub...

2020-08-11
How to prepare a small animal infection model?

How to prepare a small animal infection model?

Reproduction method Use 10 5.7 power TCID50/ml SARS-CoVBJ201 strain to infect guinea pigs, albino hamsters, black-lined hamsters, rats, brand voles and chickens via nasal drops and infectious doses: guinea pigs 0.5 ml, albino hamsters 0.2 ml , 0.2 ml...

2020-08-11
How to prepare an animal model of TCM exercise-induced fatigue?

How to prepare an animal model of TCM exercise-induced fatigue?

Use fatigue factors, rhubarb and Glauber\'s salt to relieve the effects of drugs and establish an animal model of spleen deficiency...

2020-08-11