【Animal modeling】-Establishment and applicability evaluation of animal model of pelvic organ prolapse

To establish a rat animal model that can reflect the similar pathological changes of the sacral ligament in patients with pelvic organ prolapse, to explore the effects of increasing the intensity of birth trauma and simulating menopause on the histop...

2024-04-01

【Animal Modeling】-Miniature Pig Obesity Model Induced by High Sugar and High Fat Feed

To investigate the effect of high-fat and high-sugar diet on fat distribution and blood biochemical indexes in Bama miniature pigs...

2024-04-01

【Animal modeling】-Lipopolysaccharide-induced knee joint fibroblast-like synovial cell inflammation model in SD rats and analysis of its characteristics

To establish a primary culture method of normal knee synovial cells in Sprague Dawley (SD) rats and a lipopolysaccharide-induced fibroblast-like synovial cell inflammation model...

2024-04-01

【Animal Modeling】-Comparison of the effect of gene therapy and traditional non-surgical therapy on postpartum stress urinary incontinence model rats

To study the effect of TGF-β1 gene therapy on rat model of postpartum stress urinary incontinence, and to explore the ideal new non-surgical treatment method for the disease...

2024-04-01

【Animal Modeling】-Research on the relationship between tree shrew gallstone model and substance P in digestive tract

To investigate the relationship between the establishment of tree shrew gallstone model and substance P by feeding tree shrew with high cholesterol diet...

2024-04-01

【Animal modeling】-Experimental observation of porcine circovirus type 3 infection in BALB/c mice

To study the infection of porcine circovirus type 3 in BALB/c mice...

2024-03-29

【Animal modeling】- Establishment of SD rat limb ischemia-reperfusion injury model

To introduce an improved method of blocking femoral artery blood flow in vitro, and to establish a simple, controllable and reliable model of limb ischemia-reperfusion injury in rats...

2024-03-28

【Animal modeling】-Establishment of a mouse model of salt-sensitive hypertension

To establish a mouse model of salt-sensitive hypertension, and use the antihypertensive drug nifedipine to verify the validity of the model...

2024-03-26

【Animal Modeling】-Usage-guided injection of human lung cancer cells into the left ventricle to establish a mouse model of bone metastasis

To establish a mouse model of bone metastasis by intracardiac injection of human lung cancer cells by ultrasound guidance...

2024-03-26

【Animal modeling】-Construction and application of an improved rat skull defect animal model

To explore the ideal method for constructing the rat skull defect model and improve the success rate of the animal model of bone defect...

2024-03-26

【Animal Modeling】-Monoiodoacetic acid-induced SD rat knee osteoarthritis model at different time points and disease progression

To use monoiodoacetic acid to induce a rat model of knee osteoarthritis, to detect and evaluate it at different time points, and to analyze the similarity with the pathogenesis of clinical OA...

2024-03-26

[Animal modeling] - Establishment and evaluation of chronic gastritis model in mice infected with Helicobacter pylori

To establish an animal model of Helicobacter pylori infection and evaluate the pathological changes of gastric mucosa in H. pylori associated chronic gastritis...

2024-03-26

[Animal modeling] - Establishment and evaluation of visceral hypersensitivity model in rats induced by plantar electric shock

To establish rat visceral hypersensitivity animal model by foot electric shock and evaluate its effectiveness and advantages...

2024-03-26

【Animal Modeling】-A new mouse model of severe heart disease in children

Severe childhood restrictive cardiomyopathy is a condition that causes the muscles in the walls of the heart muscle to stiffen, preventing the heart from filling properly with blood...

2024-03-25

[Animal modeling]- β- Establishment of an animal model of aortic dissection induced by aminoacetonitrile in mice

To explore β- The effect of aminoacetonitrile on the arterial wall of rats and the characteristics of human aortic dissection were compared, in order to further explore an animal model of aortic dissection that conforms to human disease characteristi...

2024-03-25

Establishment of an animal model of CA16 infection in tree shrew lung fibroblasts and expression of its receptor SCARB2

To explore the feasibility of establishing an experimental model of CA16 infection in tree shrew lung fibroblasts...

2024-03-25