[Animal modeling] - Ebola virus non human primate model

Many non-human primates have been used in the study of Ebola animal models, including African green monkeys, baboons, rhesus monkeys, and crab eating monkeys. Rhesus monkeys and crab eating monkeys are currently the most widely used, both highly sens...

2024-02-06

【Animal Modeling】-Effects of repeated hypoxic preconditioning on liver injury caused by renal ischemia-reperfusion in rats

To explore the effects of repeated hypoxic preconditioning (RHP) on liver injury caused by renal ischemia-reperfusion injury (IRI) in rats and to preliminarily explore its mechanism...

2024-01-30

【Animal Modeling】-Effect of fasting time on glucose tolerance and insulin secretion in Kunming mice

In order to explore the stable, reliable and reasonable fasting time of OGTT in Kunming mice, which are used the most in China in a specific environment...

2024-01-30

[Animal modeling]-Occupational asthma model induced by methyl toluene diisocyanate

Formaldehyde diisocyanate (TDI) is a low-molecular chemical substance with only hapten properties in the human body. TDI has obvious obvious mucosal irritation and corrosion. Exposing animals to 1.5 ppm TDI for one or several months can cause animal...

2024-01-30

【Animal modeling】-Optimization of the establishment of rat interstitial cystitis model induced by intraperitoneal injection of cyclophosphamide

To explore the ideal dose of intraperitoneal injection of cyclophosphamide to establish a rat model of interstitial cystitis...

2024-01-30

【Animal Modeling】-Analysis of the Rationality of Rabbit KOA Staging Model by Braking Method

To establish different stages of knee osteoarthritis model with plaster immobilization, in order to provide an appropriate animal model for precise treatment of acupuncture and traditional Chinese medicine...

2024-01-30

【Animal Modeling】-Comparison of the genetic structure of two experimental mouse populations using microsatellite technology

To compare the genetic structure of two experimental mouse populations using microsatellite markers...

2024-01-30

【Animal modeling】-Preliminary study on establishment of rat model of granulomatous lobular mastitis

To establish an animal model of granulomatous lobular mastitis by using the homogenate of human granulomatous lobular mastitis and the suspension of complete Freund\\\'s adjuvant...

2024-01-30

[Animal modeling] - Pancreatic kallidinogenase alleviates oxidative stress and fibrosis in rats with myocardial ischemia-reperfusion injury

To investigate the effects of pancreatic kallidinogenase on myocardial injury, oxidative stress and fibrosis in rats with myocardial ischemia reperfusion injury...

2024-01-30

【Animal Modeling】-Model of gastric ulcer caused by pyloric ligation

After the pylorus is ligated, the gastric juice remains in the stomach, and the effects of gastric acid and pepsin are enhanced. The stomach enlarges the antrum due to the pylorus ligation, and the reflex stimulates the secretion of gastrin, leading...

2024-01-30

【Animal modeling】-The phenotypic characteristics of lymphocytes in HBV transgenic mice and the effect of interferon α on them

To investigate the phenotypic characteristics of lymphocytes in hepatitis B virus (HBV) transgenic mice and the effect of interferon α on virological indexes and immune cell phenotypes...

2024-01-30

To explore an improved method for constructing aortic dissection model in mice

To explore an improved method for constructing aortic dissection model in mice...

2024-01-30

【Animal modeling】-Effect of Shenren Huoxue Granules on TGF-β1/Smad signaling pathway in carbon tetrachloride-induced hepatic fibrosis in rats

To observe the effect of Shenren Huoxue Granules on the TGF-β1/Smad signaling pathway of carbon tetrachloride-induced liver fibrosis in rats, and to explore the mechanism of Shenren Huoxue Granules in the treatment of liver fibrosis...

2024-01-30

【Animal modeling】- Guanxinning tablet inhibits myocardial cell apoptosis in chronic heart failure mice through PI3K/AKT signaling pathway

To observe the therapeutic effect of Guanxinning Tablets on chronic heart failure (CHF) mice, and to explore its action pathway from myocardial cell apoptosis and related cell signaling pathways, so as to provide experimental basis for the clinical a...

2024-01-30

【Animal Modeling】-Effects of Microbial Antioxidants on Sleep and Antioxidant Properties in Mice

To explore the effects of different doses of microbial-derived antioxidants on sleep and its antioxidant properties in mice...

2024-01-30

【Animal modeling】-Effect of Shkbp1 deletion on mouse T lymphocyte subsets

To investigate the changes of blood cell classification and T cell subsets in blood, bone marrow and spleen of Shkbp1-deficient mice (Shkbp-1-/-)...

2024-01-30