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To detect the expression of TRPC6 channel in microglia in a mouse MPTP-induced neuroinflammation model, and to explore the effect of TRPC6 channel on inflammatory expression and dopaminergic neuron damage...
2023-12-02To establish the hypertension model of Bama miniature pig with high-fat and high-salt diet and explore its possible pathogenesis...
2023-12-02To observe the morphological changes of mitochondria and the production of reactive oxygen species (ROS) in cardiac myocytes induced by electric stimulation of bupivacaine, and to establish an ideal model of rat cardiac myocytes poisoned by bupivacai...
2023-12-02To establish an animal model of oral ulcer in SD rats by different chemical burning methods and screen the best scheme for the evaluation of therapeutic effect...
2023-12-02To analyze the differentially expressed genes in the prefrontal cortex of Alzheimer\\\'s disease (AD) model mice and reveal the pathogenesis of AD from the transcriptome level...
2023-12-02Animal models are the key to the study of serious infectious diseases, and are of great significance to determine the pathogenesis of the disease and develop vaccines and drugs...
2023-11-30To investigate the effects of pancreatic kallidinogenase on myocardial injury, oxidative stress and fibrosis in rats with myocardial ischemia reperfusion injury...
2023-11-30Founder α⁃ Parkinson\\\\\\\'s disease model of transgenic rats with synaptonuclein A30P mutant...
2023-11-30To establish a rat model of acute lung injury (ALI) induced by smoke inhalation from ship fire with multiple composite materials as combustor and temperature controlled...
2023-11-30Groundhog, also known as marmot. The average weight of a groundhog is 4.5kg, and it can grow up to 6.5kg at most, with a body length of approximately 56cm. The groundhog is mainly distributed in the grasslands of North America to Canada and other reg...
2023-11-27Renal vascular hypertension is the most common secondary hypertension caused by narrowing or obstruction of one or both renal artery trunks or branches, resulting in reduced renal vascular flow and renal ischemia. Renal vascular hypertension accounts...
2023-11-27he KK mouse was successfully cultivated in 1957 by Japan\'s Konteng family using the original Japanese mouse (also known as the \"twenty day mouse\"). In 1962, Nakamura reported that KK mice had similar properties to adult obese diabetes, w...
2023-11-27Select female rat offspring born at the same time period for selective breeding. On the 8th day of age, female rats were subcutaneously injected with testosterone propionate at a dose of 1.25mg/animal in the neck and back, and weaned on the 22nd day ...
2023-11-27To investigate the effect of astragaloside Ⅱ on the interleukin-21 ( IL-21 ) / signal transducer and activator of transcription 3 ( STAT3 ) pathway and airway inflammation in juvenile asthmatic rats...
2023-11-27Spontaneous hypertensive rats are inbred Wistar rats cultivated by Okamoto and Aoki in 1963 and their control inbred Wistar Kyoto rats. The onset of hypertension in SHR rats is related to an increase in cardiac output. As hypertension progresses, car...
2023-11-23High altitude polycythemia (referred to as \"hypererythrosis\") is a chronic high altitude disease caused by excessive compensatory proliferation of red blood cells (i.e., excessive proliferation of red blood cells) caused by high altitude ...
2023-11-23