[[Animal modeling - efficacy evaluation] - primary diabetes BB rats

BB Wistar rat is a spontaneous diabetes animal model...

2024-08-06

[Animal Modeling - Efficacy Evaluation] - Mongolian Sand Rat Helicobacter pylori Model

5-week-old male Mongolian sand rats without specific pathogen grade were fed standard feed and sterilized water with libitum...

2024-08-06

[Animal Modeling - Pharmacological Evaluation] - Penicillin induced Epilepsy Animal Model

SD rats, half male and half female, weighing (300 ± 20) g; Drug: Penicillin...

2024-08-06

[Animal Modeling Drug Efficacy Evaluation] - Rabbit Pseudomonas aeruginosa Pneumonia Model

Select a small amount of mucinous PA colonies stored at 4 ℃, incubate them in MH broth at 37 ℃ for 24 hours, and prepare a bacterial suspension of 0.5 units using MH broth. Freshly prepare on the same day of use. New Zealand rabbits aged from 18 to 2...

2024-08-06

【Animal modeling - Drug efficacy evaluation】 - Cortical injection of ferrous chloride to establish a traumatic epilepsy animal model

Healthy adult male SD rats weighing 180-220g; Drug: 10% chloral hydrate, FeCl2 solution...

2024-08-06

[Animal Modeling Drug Efficacy Evaluation] - Rhesus Monkey HGV Infection Model

Experimental rhesus monkeys weighing 2.5-6.5kg and aged 2-8 years were selected. Prior to infection, ALT enzyme activity was detected to be normal, and liver biopsy showed no dynamic liver pathological changes...

2024-08-05

[Animal Modeling - Pharmacological Evaluation] - Model of Memory Consolidation Disorder Caused by Electric Shock

Wistar rats, weighing (216 ± 10) g; Instrument: Electroconvulsive device...

2024-08-05

[Animal Modeling - Pharmacological Evaluation] - Model of Memory Consolidation Disorder Caused by Brain Hypoxia

mouse; Drug: a mixture of 96.2% N2 and 3.8% O2 gas, pure CO2, NaNO2; Instrument: a sealed jar...

2024-08-05

[Animal Modeling - Efficacy Evaluation] - Foot and Mouth Disease Virus Animal Model

Dilute the foot-and-mouth disease virus ORMF8 with 0.01mol/L PBS (pH 7.4) to an LD50 of 10-3 to 10-7/0.2ml, and then inject each titer of virus solution intradermally through the hind limb toes of guinea pigs, with an injection dose of 0.2ml per anim...

2024-08-05

【Animal Modeling - Pharmacological Evaluation】 - Tree Shrew Hepatitis B Model

Tree shrews were inoculated via femoral vein with 0.5ml of serum from hepatitis B patients with positive hepatitis B B virus surface antigen (HBsAg) and hepatitis B B virus e antigen (HBeAg)...

2024-08-05

[Animal modeling - Drug efficacy evaluation] - Pulmonary heart disease

Select adult Japanese large eared rabbits and inject a 1% mass fraction of ferric chloride aqueous solution into the rabbit ear vein. Inject 0.5ml twice a week from week 1 to week 4; From the 5th to the 6th week, twice a week, 0.75ml each time; In th...

2024-08-05

[Animal Modeling - Pharmacological Evaluation]- Depression Models in Solitary or Separate Care

Some primates or non primates may exhibit characteristic symptoms such as agitation, sleep disorders, and lamenting after separation from their offspring...

2024-08-05

[Animal Modeling Drug Efficacy Evaluation ]- Heymann Nephritis Model in Rats

rats, weighing 150-200g; Drug: Complete Freund\'s adjuvant, physiological saline...

2024-08-05

[Animal Modeling - Pharmacological Evaluation] - Ovarian Resection Induced Osteoporosis Animal Model

Primary osteoporosis includes postmenopausal osteoporosis and senile osteoporosis, mainly characterized by decreased bone mass, degeneration of bone microstructure, decreased bone strength and increased fragility, and susceptibility to fractures...

2024-08-02

[Animal Modeling - Pharmacological Evaluation] - Corticosteroid Induced Osteoporosis Animal Model

The extensive use of glucocorticoids can cause calcium and phosphorus metabolism disorders in animal bodies, reduce the transformation of pre osteoblasts into functional osteoblasts, directly inhibit osteoblast function, reduce collagen synthesis, re...

2024-08-02

[Animal Modeling - Pharmacological Evaluation] - Allogeneic Bone Tumor Animal Model

Allogeneic transplantation refers to the transplantation of the same or homologous animal species. The commonality between the donor and recipient is significant, making it easy to stay in the body, grow and reproduce, and reproduce the tumor process...

2024-08-02