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Eye hypersensitivity is mainly a type I hypersensitivity reaction mediated by mast cells. Hay fever conjunctivitis, vernal keratoconjunctivitis, atopic keratoconjunctivitis, and macromastic keratoconjunctivitis are mainly involved in type I allergic ...
2024-08-02Corneal injury can be divided into damage to the corneal endothelium and damage to the corneal epithelium and stroma according to different levels...
2024-08-02Dry eye disease, also known as dry keratoconjunctivitis, is one of the most common eye diseases, which can cause damage to the ocular surface and blurred vision, affecting the quality of life of patients...
2024-08-02This type of cataract model forms cataracts by affecting the substance metabolism of the crystalline lens through various drugs, commonly used including D-galactose, sodium selenate, naphthalene, and glucocorticoids, as well as less commonly used dru...
2024-08-02The chronic epilepsy model can reflect the initiation, development, and accompanying pathological and physiological changes in the brain during epileptic seizures. This provides a foundation for further research on epilepsy. According to the intensit...
2024-08-02The most common viral keratitis is herpes simplex virus keratitis. HSK is a blinding eye disease caused by herpes simplex virus infection, which seriously endangers patients\' visual function. Its clinical characteristics are mainly characterized by ...
2024-08-02The occurrence of obesity is the result of energy metabolism disorders in the body, and its exact pathogenesis is not fully understood. Currently, it is believed to be related to genetics, central nervous system abnormalities, endocrine dysfunction, ...
2024-08-02In 1975, Lomobardi et al. established a female mouse model of acute hemorrhagic necrotizing pancreatitis by feeding a choline deficient diet supplemented with ethionine...
2024-08-02At present, animal models of hepatitis B virus mainly include tree shrew hepatitis B model, duck hepatitis B model, marmot hepatitis B model, and mouse hepatitis B model...
2024-08-02Hepatitis E is mainly transmitted through the fecal oral route (digestive tract), while other routes include blood transmission and vertical transmission...
2024-08-02In the process of early diagnosis and treatment of pancreatic cancer, it is found that the precancerous lesions of pancreatic cancer, pancreatic intraductal epithelioma, molecular genetic abnormalities, are directly related to pancreatic cancer...
2024-08-02By using genetic engineering methods to introduce specific exogenous genes into the genome of animals, they can undergo integration, genetic reproduction, and thus cultivate animals carrying exogenous genes...
2024-08-02A liver cancer model formed by transplanting liver cancer tissue, cell lines, or other malignant tumors derived from animals or humans into animal bodies in the future...
2024-08-02Induced liver cancer animal model refers to the use of chemical, physical, and biological carcinogenic factors on experimental animals to simulate the cyclic changes of liver injury fibrosis malignant transformation, and induce the formation of liver...
2024-08-02Removing the right kidney and clipping the left renal artery causes ischemic mitochondrial dysfunction in the kidney, resulting in the production of a large amount of hypoxanthine. Under hypoxic conditions, hypoxanthine cannot be metabolized into xan...
2024-08-01Chronic obstructive pulmonary disease (COPD) is a chronic respiratory system disease characterized by airflow limitation, with inflammation as the core. It is related to abnormal inflammatory responses of the lungs to harmful gases or particles such ...
2024-08-01