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![[Animal modeling - Pharmacodynamic evaluation] - Chemical induced cardiogenic shock](/./uploads/images/default/default.png)
Cats can be used as a cardiogenic shock model when their blood pressure drops below half of the normal value due to slow femoral vein injection of 3% pentobarbital under the anesthesia and artificial respiration conditions of Ultan...
2024-07-01Adult SD rats were instilled with Aspergillus fumigatus suspension through tracheal intubation to establish a rat lung infection model. The suspension of Aspergillus fumigatus was inoculated into the rats through nasal and oropharyngeal instillation ...
2024-07-0112 week old male Wistar rats, weighing 250-300g; Medication: Anesthetics; Instruments: rat stereotactic device, miniature electrocoagulation knife, electric pulse random stimulation device...
2024-07-01This model is commonly used in China. Huang et al. applied 5% propranolol to the ear of guinea pigs (350-400g) and 0.3g of the drug (1cm2) twice a day for 2 consecutive weeks. At the same time, 1% dinitrochlorobenzene (DNCB) and 1% croton oil castor ...
2024-07-01Adult rats, regardless of gender, weighing 250-400g; Medications: physiological saline, formaldehyde...
2024-07-01Adult rats were stimulated with sulfur dioxide at a dose of (200-250) x 10 to the power of -5, for 1 hour per day and continuous stimulation for 13 days. Cold wind stimulation was used with a temperature 5 ℃ lower than the living environment temperat...
2024-07-01Put 20-50g/L of degraded carrageenan solution into a bottle for guinea pigs to drink, record the amount of water the guinea pigs drink, and add sucrose at a rate of 50g/L to increase palatability...
2024-07-01Female BALB/c mice (H-2 gene phenotype), aged 8-10 weeks at the time of use; Reagents and antibodies: Hamster anti mouse CD3 monoclonal antibody, fluorescein isothiocyanate (FITC) labeled anti mouse CD45RB monoclonal antibody, phycoerythrin (PE) labe...
2024-07-01Closed group small pigs, weighing 15.5-43.0kg, 2-3 months old, with similar body weights for both donors and recipients, regardless of gender. They were fasted for 24 and 6 hours before surgery, and water was prohibited. They were randomly divided in...
2024-07-01Adult rabbits were fixed on a rabbit platform, and a lever pressure device was used to apply 7.5kg of pressure on the inner thigh muscle of the right hind limb for 1.5 hours. The changes in muscle temperature, leg diameter, hind limb blood flow, conj...
2024-07-01Prepare a BCG vaccine solution with physiological saline to contain 10 times the power of live bacteria per milliliter, and inject 0.2ml (2.5mg) of BCG vaccine solution through the tail vein. 10 days later, 0.2ml (10 μ g) of LPS physiological saline ...
2024-07-01For the first 3 days, rats were given a 2% sucrose solution for free consumption. Then, 5% alcohol was added to the sucrose solution, and the alcohol concentration was increased by 5% to 15% every 4 days. Afterwards, the alcohol concentration was inc...
2024-07-01Adult mice, good at calling ferocious cats. When raising mice to the age of 75 days, they were mated in a ratio of 2:1 male and female. On the evening of the 4th day, male mice were taken out, and on the 5th day, the experimental mice were intimidate...
2024-07-01The content of 3 β - HSD and glucose-6-phosphate dehydrogenase (G-6-PD) in the interstitial cells of the testes of elderly animals, as well as the content of 3 β - HSD in the adrenal cortex, significantly decreased...
2024-07-01Feed rats with liquid feed containing total nutrients and alcohol. This food is formulated based on calories, with 21% fat, 18% protein, 47% carbohydrates (36% of which are replaced by alcohol), as well as some vitamins and inorganic salts. Solid foo...
2024-07-01Rats were fed liquid feed containing total nutrients and alcohol with pyrazole for 12 weeks...
2024-07-01