[Animal modeling] - establishment of a mouse model of hypothyroidism

To verify the success of modeling hypothyroidism in C57BL/6 and KM mice after total thyroidectomy using two different surgical methods, and to compare the differences in success rates among different surgical methods...

2024-04-09

【 Animal modeling 】 - The effect of Qinji Liangxue mixture on similar animal models of hemorrhoid disease

To explore the mechanism of Qinji Liangxue mixture in combating hemorrhoids...

2024-04-09

[Animal modeling] - Establishment of rat gastritis cancer transformation model and exploration of early diagnosis methods

To construct a rat model of gastritis and cancer transformation and explore new early serodiagnostic indicators of gastric cancer...

2024-04-08

【Animal Modeling】-Comparison of different methods of making visceral hypersensitivity models of irritable bowel syndrome

To study different methods to make IBS visceral hypersensitivity mouse model, and to evaluate its visceral sensitivity and stability...

2024-04-08

【Animal Modeling】-Construction and research of eukaryotic expression vector of full-length and mature IL-37b

Construct the eukaryotic expression vector pEGFPN1/IL-37b of full-length mature IL-37b, and detect its expression in RAW264.7 cells...

2024-04-08

【Animal modeling】-Isolation, culture and identification of goat alveolar macrophages

To establish a high-purity method for separating and culturing alveolar macrophages, and to provide materials for studying the biological characteristics of macrophages and the survival mechanism of intracellular parasites...

2024-04-07

[Animal modeling] - Comparison of insulin resistance atherosclerosis models between white haired black eyed rabbits and Japanese big ear white rabbits

To investigate the phenotypic difference and pathological mechanism of insulin resistance atherosclerosis models in white haired black eye (WHBE) rabbits and Japanese big ear white (JW) rabbits...

2024-04-07

【 Animal Modeling 】 - Constructing an Experimental Autoimmune Myasthenia Gravis Mouse Model Using the Black Spot Double Fined Torpedo

To establish an experimental autoimmune myasthenia gravis animal model that meets international preclinical experimental standards...

2024-04-07

【Animal modeling】-Experimental study on the preparation of SD rat portal hypertension animal model by ligation of left branch

To explore whether simple left portal vein ligation can form stable portal hypertension and whether nitric oxide plays a corresponding role in it...

2024-04-03

【Animal modeling】-Effect of hypoxia on the expressions of drug transporters MDR1 and MRP2 in rats

To study the effects of simulated rapid altitude hypoxia on some physiological indexes and the expressions of MDR1 and MRP2 efflux drug transporters in the small intestine, liver and kidney of rats, and to preliminarily explore the effect of high alt...

2024-04-03

[Animal modeling] - Comparison of insulin resistance atherosclerosis models between white haired black eye rabbits and Japanese big ear rabbits

To investigate the phenotypic difference and pathological mechanism of insulin resistance atherosclerosis models in white haired black eyed (WHBE) rabbits and Japanese white eared (JW) rabbits...

2024-04-02

【Animal Modeling】-Using the seasonal influenza virus H3N2 mouse-adapted strain to establish a mouse model

To establish a mouse model with the seasonal influenza virus H3N2 mouse-adapted strain, and to describe the molecular mechanism of the adaptation to the change of the virulence of the strain...

2024-04-02

【Animal modeling】-The scavenging effect of arginine antidiuretic hormone on pulmonary edema in rats with acute lung injury

To investigate the effect of arginine antidiuretic hormone (AVP) on pulmonary edema fluid clearance in patients with acute lung injury...

2024-04-02

【Animal modeling】-Effect of cigarette smoke exposure on plasma nicotine and cotinine in male rats

To investigate the internal exposure level of cigarettes in vivo by measuring the plasma nicotine and cotinine contents in smoking rats...

2024-04-02

【Animal Modeling】-Effect of high-fat diet-induced obesity on ovarian function in female reproductive rats

To evaluate the effect of high-fat diet-induced obesity on ovarian function in female rats, and to explore its mechanism...

2024-04-01

【Animal modeling】-Quantitative analysis of liver tumors in BALB/c mutant curly mice based on Image J software

To investigate the differences between BALB/c mutant curly-haired mice and normal BALB/c mice to construct tumor models via portal vein injection, and to establish a quantitative analysis method of tumor images based on Image J software...

2024-04-01