[Animal Modeling] - Establishment and Evaluation of a Constipated Irritable Bowel Syndrome Model with Liver Depression Syndrome

To establish a rat model of superior mesenteric vein thrombosis using ligation method, simulate the pathological process of the disease, and provide basic preparation for studying its pathogenesis and treatment methods...

2024-03-02

[Animal modeling] - establishment of chronic myocardial ischemia model in miniature pigs and application of non-invasive telemetry technology

In response to the shortcomings of previous models of chronic myocardial ischemia in pigs, this study first investigated the mechanism of hyperlipidemia leading to AS and causing coronary artery obstruction or stenosis. A high-fat diet was used to in...

2024-03-02

[Animal modeling]- Application evaluation of continuous glucose monitoring system in rabbit hypoglycemia model

To establish a rabbit hypoglycemia model and evaluate the accuracy and timeliness of subcutaneous continuous glucose monitoring system in hypoglycemia monitoring...

2024-03-02

[Animal modeling] - comparative analysis of three models of chicken embryo chorioallantoic membrane transplantation tumors

To compare the growth of three different cancer cell lines on the chorioallantoic membrane of chicken embryos, select the best transplantation cancer cell line, establish a transplantation tumor model, and observe its biological characteristics...

2024-03-02

[Animal modeling] - Application of targeted near-infrared fluorescent dyes in liver cancer model research

To explore the application of the near-infrared fluorescent dye IR-783 of heptamethrin in imaging research of liver cancer models, and analyze the molecular mechanism of the dye targeting tumor cells...

2024-03-02

[Animal modeling] - Prophylactic administration of all trans retinoic acid can alleviate inflammation in rheumatoid arthritis model rats

To explore the effects of all trans retinoic acid (ATRA) on the joint tissue structure, serum expression levels of inflammatory cytokines, and expression levels of cartilage injury related proteins during the formation phase of type II collagen (CIA)...

2024-03-02

Construction of an animal model of chronic simple lichen in the external genitalia of SD rats and expression of protease activated receptor 2

To establish an animal model of chronic simple lichen in the external genitalia of SD rats, study the expression of protease activated receptor 2 in the model rat external genitalia skin lesions, and provide an ideal animal model for LSC...

2024-03-02

[Animal modeling] - establishment of a mouse model of skin adverse reactions induced by erlotinib

Erlotinib is a novel targeted drug for the treatment of non-small cell lung cancer. It has been widely used in clinical practice in recent years, but has many side effects, with rash being the most common and difficult for patients to accept...

2024-03-02

[Animal Modeling] - Establishment of an Infectious Model of Coxsackie Virus A16 and Evaluation of Related Immunological Indicators and Applications

To establish a simple and reliable small rodent experimental animal model sensitive to Coxsackie virus A16 type...

2024-03-02

[Animal Modeling] - Validation and Regularity Exploration of Establishing a Hyperlipidemia Model with High Fat Diet Feeding

To establish hyperlipidemia in SD rats fed with a high-fat diet for 8 weeks, verify the feasibility of the modeling method, and explore the changes in blood lipids of rats at different time points...

2024-03-02

[Animal Modeling] - Application Progress of Targeted Gene Modification Technology in Immunodeficiency Animal Model Research

　　Immunodeficiency animal models have important applications in human related disease mechanism research, drug development, organ transplantation research, and stem cell research...

2024-03-02

[Animal Modeling] - Application of Gene Modified Animal Models to Study the Progress of Depression

Depression is a complex mental disease with polygene inheritance. Its incidence rate is high, and the serious cases are accompanied by suicide...

2024-03-02

[Animal modeling] - Establishment of a mouse model of abdominal aortic aneurysm and analysis of its histological characteristics

To establish an abdominal aortic aneurysm model in C57BL/6J mice by perfusion of porcine trypsin and evaluate its pathological changes...

2024-03-01

【Animal modeling】-Establishment and application of multiplex PCR method for four pathogens in experimental animals

To establish a multiplex PCR method for the rapid detection of four experimental animal pathogens, Pasteurella multocida, Bordetella bronchiscus, Mycoplasma and Klebsiella pneumoniae...

2024-03-01

【Animal modeling】- PERV-env gene cloning and tissue expression profiling in Guangxi Bama miniature pigs

To clone part of PERV-env gene of Guangxi Bama miniature pig, and study its expression difference in different tissues...

2024-03-01

【Animal Modeling】-Relationship between the expression of vitamin D metabolizing enzyme CYP24A1 in testis of adult tree shrew and fertility

To study the transcript levels of vitamin D metabolizing enzymes and vitamin D receptors in the testis of adult tree shrew, detect the protein expression of CYP24A1, and explore the causes of reproductive disorders in male experimental tree shrew...

2024-03-01