[Animal modeling] - Improvement and evaluation of conditions of rat model of myocardial hypertrophy induced by isoproterenol based on implantable osmotic pump

Myocardial hypertrophy is an effective compensatory function with slow development, an adaptive response to hemodynamics or myocardial injury, and an independent risk factor leading to heart failure...

2023-09-22

[Animal Modeling] - Animal Model of Lung Qi Deficiency Syndrome by Smoking Method

Adult rats or rabbits were placed in a smoke chamber with a volume of 1m3. 30-50g of shavings, sawdust, and tobacco were ignited and smoked once a day for 30 minutes each time. The smoking time of the rabbits was doubled, and their symptoms and signs...

2023-09-22

[Animal modeling] - Establishment, identification and preliminary phenotype of oligodendrocyte conditionally knockout FGF9 gene mouse model

To establish oligodendrocyte specific knockout fibroblast growth factor 9 (FGF9) mouse model and further study the role of FGF9 in neural development...

2023-09-22

【Animal modeling】-Establishment of acute and chronic hyperuricemia models

To establish acute mouse and chronic rat hyperuricemia models, and use positive drugs to verify the curability of the two models, so as to provide model tools for the development of anti-hyperuric acid drugs...

2023-09-22

【Animal Modeling】-Study on Periodic Lesion of Chronic Liver Injury in Mice

To study the characteristics of liver injury in a mouse model of chronic liver disease induced by carbon tetroxide (CCL4), and to explore its application in medical research...

2023-09-22

[Animal modeling] - protective effect of paeoniflorin on nerve injury in rats with acute cerebral infarction by activating LKB1/AMPK signal pathway

To investigate the protective effect of paeoniflorin on nerve injury in rats with acute cerebral infarction by activating hepatic kinase B1 (LKB1)/5 \\\'- adenosine phosphate activated protein kinase (AMPK) signal pathway...

2023-09-22

【Animal Modeling】-Effect of plantar shock stress duration on anxiety-like behavior in rats

To observe the effects of plantar shock stress duration on the elevated plus maze and anxiety-like behaviors in the opening test in rats...

2023-09-21

【Animal Modeling】-Radiation Pulmonary Fibrosis Model

Radiotherapy is one of the main treatment methods for breast tumors. Radiation pulmonary fibrosis is a common lung injury repair change after radiotherapy of breast tumors, which may lead to irreversible lung dysfunction...

2023-09-21

[animal modeling] - systematic evaluation of the effect of placental differentially expressed proteins on the growth and development of placenta in rat model of gestational diabetes

to systematically evaluate the effects of placenta differentially expressed proteins on the growth and development of placenta in diabetes of pregnancy (GDM) rat model...

2023-09-19

【Animal modeling】-5-Fluorouracil combined with mechanical scratching-induced oral mucositis model in golden hamsters

To establish a model of oral mucositis in golden hamsters induced by 5-fluorouracil combined with mechanical scratching...

2023-09-19

[Animal Modeling]-Effect of Curcumin on Rat Intestinal Mucosal Damage and Oxidative Stress in Desert Dry and Hot Environment

To explore the protective effect of curcumin pretreatment on rat intestinal mucosa in desert, dry and hot environments...

2023-09-19

【Animal Modeling】-Establishment and rapid detection of an animal model of immunocompromised mice

To quickly establish an animal model of KM mice with low immunity, and use a simple and rapid method to identify the establishment of the animal model...

2023-09-19

[Animal modeling] - Leptin regulates the signal transduction of liver fibrosis in rats and the intervention of mistletoe alkaloid

To investigate the signal transduction mechanism of leptin in regulating liver fibrosis in rats and the intervention effect of mistletine...

2023-09-18

[Animal modeling] - Intervention of resveratrol on premature ovarian failure in mice and its possible mechanism

To observe the intervention effect of resveratrol on premature ovarian failure in mice and elucidate its possible mechanism...

2023-09-18

【Animal modeling】-The effect of DHEA on superovulation and oocyte quality in mice

To study the effect of dehydroepiandrosterone (DHEA) on superovulation and oocyte quality in C57BL/6J female mice and its mechanism...

2023-09-18

[Animal modeling] - Establishment and analysis of conditioned staphylococcus aureus arthritis mouse model

To establish and analyze the arthritis model infected by conditionally infected Staphylococcus aureus, so as to provide an animal model for the research of arthritis mechanism and drug development...

2023-09-18