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Model rats were anesthetized by intraperitoneal injection of pentobarbital at a dose of 30mg/kg, followed by skin disinfection with iodine. After laparotomy, the stomach and upper jejunum were exposed, and the anterior stomach was fixed together with...
2023-09-13Application of propranolol to create a guinea pig ear psoriasis model. This model is commonly used in China. Huang et al. applied 5% propranolol to the ears of guinea pigs (350-400g) (0.3g of drug per cm2) twice a day for 2 weeks, while using 1% dini...
2023-09-13Animal modeling materials: Adult rats, male and female, weighing 200-250g; Drugs: 2,4-dinitrochlorobenzene, acetone, acetic acid, ethanol; Instrument: 3mm diameter nylon catheter...
2023-09-12Reproduction method: Adult rats were gavaged with 4 ℃ vinegar daily, with a volume of 10ml/kg body weight for 10 consecutive days. During this period, observe changes in animal appearance and behavior, weight, food intake, and water intake. On the da...
2023-09-12Reproduction method: Adult rats were raised in a single cage and subjected to external abdominal irradiation at a dose of 250 rad/min. The first dose was followed by a second dose of enhancement 7 days after the first dose. The changes in food intake...
2023-09-12Toll like receptor 2 gene knockout mice. In Toll like receptor 2 gene knockout mice, homozygotes can survive with normal appearance and behavior. Macrophages from mouse bone marrow cannot stimulate immune responses to lipoproteins of Borrelia burgdor...
2023-09-12Reproduction method: Adult rats were raised in a single cage, and the experimental rat cage was fixed to the oscillator using a tray. The oscillator was controlled by a relay to stop for 10 minutes every 20 minutes of vibration, with an average of 10...
2023-09-12The homozygous CD4 antigen knockout mice cannot express CD4 on the cell surface. CD8+T cells and myeloid components develop normally. This indicates that expression in ancestral cells and CD4+CD8+thymocytes is not necessary. The antiviral activity of...
2023-09-12Reproduction method: Adult rats were raised in a single cage and given a sufficient amount of medicated feed (rhubarb, mirabilite, and standard feed materials were evenly mixed in a ratio of 0.85:0.15:9.0 to make medicated feed, with 0.1g of raw medi...
2023-09-12Gene knockout mice with B cell defects. In B cell deficient Igh-6 gene knockout mice, homozygotes lack mature B cells and cannot express membrane bound IgM. This mouse is mainly used to study the function of B cells in the immune system. For example,...
2023-09-12Reproduction method: Adult rats were orally gavaged with Shanxi white vinegar at a dose of 10ml/kg body weight for 10 consecutive days. Observe changes in food intake, spontaneous activity, body weight, rectal temperature, stool characteristics, and ...
2023-09-12The purpose of this study is to investigate whether the animal nasal aerosol exposure device can operate normally and generate aerosol particles with a specific particle size, and to explore the air tightness, distribution uniformity and disinfection...
2023-09-11To preliminarily investigate the effect of intermittent hypoxic preconditioning on epileptic seizures in rats induced by lithium chloride and pilocarpine and its brain protective mechanism...
2023-09-11To detect the correlation between the SNP locus of SLCIA2 gene and the activity of Labrador retrievers and golden retrievers, in order to screen effective genetic molecular markers for the early selection and breeding of guide dogs...
2023-09-11To understand the changes of estrogen, progesterone, prolactin in plasma and prolactin and prolactin receptor mRNA levels in male green fluorescent nude mice in different pregnancy and lactation periods...
2023-09-11To study the occurrence of vascular calcification in aged rats, and the changes of osteopontin and osteocalcin expression in the arterial vessel wall of aged rats...
2023-09-11