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【Animal modeling】-Effect of curcumin on blood and tissue neutrophils in rats with heat stroke in desert dry heat environment

【Animal modeling】-Effect of curcumin on blood and tissue neutrophils in rats with heat stroke in desert dry heat environment

To investigate the effect of curcumin pretreatment on the changes of blood and tissue neutrophils in rats with heat stroke in desert dry heat environment...

2022-07-11
【Animal Modeling】-Expression of Perilipin in Kidney Tissue of Rats with Diabetic Nephropathy

【Animal Modeling】-Expression of Perilipin in Kidney Tissue of Rats with Diabetic Nephropathy

To observe the characteristics of rat diabetic nephropathy model and the diagnostic value of urinary LN for early DN, and to explore the expression of perilipin (Plin) in the kidneys of DN rats...

2022-07-11
【Animal Modeling】-Therapeutic effect of puerarin on acute liver failure in mice and its mechanism of action

【Animal Modeling】-Therapeutic effect of puerarin on acute liver failure in mice and its mechanism of action

To investigate the protective effect of puerarin on D-galactosamine-induced acute liver failure (ALF) in mice and to preliminarily observe its mechanism...

2022-07-11
【Animal Modeling】-Effect of psycho-dependent heroin on embryonic development and Bax expression in brain tissue of rats

【Animal Modeling】-Effect of psycho-dependent heroin on embryonic development and Bax expression in brain tissue of rats

To investigate the effect of heroin, a psychotropic substance, on the development of embryonic rats and the expression of Bax in the brain...

2022-07-11
【Animal Modeling】-Effect of total alkaloids of Dendrobium officinale on insulin resistance in diabetic rats with non-alcoholic fatty liver disease

【Animal Modeling】-Effect of total alkaloids of Dendrobium officinale on insulin resistance in diabetic rats with non-alcoholic fatty liver disease

To study the effect of total alkaloids of Dendrobium officinale on insulin resistance in diabetic rats with non-alcoholic fatty liver disease (NAFLD)...

2022-07-11
【Animal Modeling】-The effect of rapid modeling of KK mouse diet on related indicators of KK/Upj-Ay/J mice

【Animal Modeling】-The effect of rapid modeling of KK mouse diet on related indicators of KK/Upj-Ay/J mice

To study the rapid modeling of KK mouse diet and its effect on related indexes in KK/Upj-Ay/J mice...

2022-07-11
【Animal modeling】-Effect of lamotrigine on the expression of PGP, MVP and amino acid content in the hippocampus of chronic epilepsy rats

【Animal modeling】-Effect of lamotrigine on the expression of PGP, MVP and amino acid content in the hippocampus of chronic epilepsy rats

To investigate the effect of lamotrigine on the expression and amino acid content of P-glycoprotein and main vault protein in the hippocampus of chronic epilepsy rats...

2022-07-11
【Animal Modeling】-Protein Transformation Regulation Mechanism of Rat Skeletal Muscle Atrophy Induced by Hypoxia Exposure

【Animal Modeling】-Protein Transformation Regulation Mechanism of Rat Skeletal Muscle Atrophy Induced by Hypoxia Exposure

To compare the differences in the expression of genes related to protein synthesis and decomposition in skeletal muscle of rats under hypoxic exposure and paired hypoxic feeding intervention (semi-starvation state) under normoxia, in order to explore...

2022-07-11
【Animal Modeling】-Effect of fasting time on glucose tolerance and insulin secretion in Kunming mice

【Animal Modeling】-Effect of fasting time on glucose tolerance and insulin secretion in Kunming mice

In order to explore the stable, reliable and reasonable fasting time of OGTT in Kunming mice, which are used the most in China in a specific environment...

2022-07-11
【Animal Modeling】-Human umbilical cord mesenchymal stem cell transplantation repairs premature ovarian failure in rats

【Animal Modeling】-Human umbilical cord mesenchymal stem cell transplantation repairs premature ovarian failure in rats

To investigate the mechanism of human umbilical cord mesenchymal stem cell transplantation in repairing ovarian function in rats with premature ovarian failure...

2022-07-11
【Animal Modeling】-Effects of Different Exercise Mode Interventions on Emotional Behavior in Aggressive Rats

【Animal Modeling】-Effects of Different Exercise Mode Interventions on Emotional Behavior in Aggressive Rats

To investigate the effects of different exercise interventions on emotional behavior of aggressive rats...

2022-07-08
【Animal modeling】-Discuss the protective effect and mechanism of activated protein C on myocardial ischemia-reperfusion injury in rats

【Animal modeling】-Discuss the protective effect and mechanism of activated protein C on myocardial ischemia-reperfusion injury in rats

To investigate the protective effect and mechanism of activated protein C (APC) on myocardial ischemia-reperfusion injury in rats...

2022-07-08
【Animal Modeling】-Effect of hypoxia training on Ghrelin-GHSR pathway in obese mice

【Animal Modeling】-Effect of hypoxia training on Ghrelin-GHSR pathway in obese mice

To apply hypoxic training to obese mice to observe the changes of GHSR levels in gastric tissue and hypothalamus, so as to explore whether hypoxic training affects the Ghrelin-GHSR pathway to improve obesity...

2022-07-08
【Animal modeling】-Observation of the effect of thrombopoietin on cardiomyocyte apoptosis in rats with heart failure induced by adriamycin based on TGF-β1/Smad3 signaling pathway

【Animal modeling】-Observation of the effect of thrombopoietin on cardiomyocyte apoptosis in rats with heart failure induced by adriamycin based on TGF-β1/Smad3 signaling pathway

To investigate the effect of thrombopoietin (TPO) on cardiomyocyte apoptosis in rats with adriamycin-induced heart failure (CHF) and its regulatory mechanism on TGF-β1/Smad3 signal...

2022-07-08
【Animal modeling】-Study on the protective effect of curcumin on cognitive function and neurological function in mice with cerebral ischemia-reperfusion injury

【Animal modeling】-Study on the protective effect of curcumin on cognitive function and neurological function in mice with cerebral ischemia-reperfusion injury

To investigate the effect of curcumin on cognitive function, neurological function and mechanism of cerebral ischemia-reperfusion injury in mice...

2022-07-08
【Animal modeling】-Effect of hydroxychloroquine on spleen lymphocytes in lupus mice

【Animal modeling】-Effect of hydroxychloroquine on spleen lymphocytes in lupus mice

To observe the effect of hydroxychloroquine on the distribution of lymphocytes in peripheral immune organs (spleen) of mice with systemic lupus erythematosus (TC mice)...

2022-07-08