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【Animal modeling】-Effect of Oct4 and Cdx2 on the differentiation of bovine embryo inner cell mass and trophectoderm

【Animal modeling】-Effect of Oct4 and Cdx2 on the differentiation of bovine embryo inner cell mass and trophectoderm

To investigate the effects of Oct4 and Cdx2 knockdown on the expression of genes related to the differentiation of bovine ICM and TE, and to explain the roles of Oct4 and Cdx2 in the early development of bovine embryos...

2022-05-31
【Animal Modeling】-Effects of Unpredictable Stress Stimulation on the Immunity and Microflora of the Gastrointestinal Tract in Rats

【Animal Modeling】-Effects of Unpredictable Stress Stimulation on the Immunity and Microflora of the Gastrointestinal Tract in Rats

To analyze the effects of unpredictable stress on the gastrointestinal immune system and microbial population by observing the rats after 9 days of unpredictable stress stimulation, so as to provide reference for the study of chronic stress on gastro...

2022-05-31
【Animal modeling】-Effect of different bedding materials on learning and memory ability of SPF KM mice

【Animal modeling】-Effect of different bedding materials on learning and memory ability of SPF KM mice

To investigate the effect of non-professional processing wheat straw litter, corncob litter, shavings litter and paper litter on the learning and memory ability of SPF Kunming mice (KM), and the effect of different litter on the behavior of mice. inf...

2022-05-31
【Animal Modeling】-Corticosterone-induced Depression in Mice Associated with Learning and Memory Impairment

【Animal Modeling】-Corticosterone-induced Depression in Mice Associated with Learning and Memory Impairment

To study the effects of chronic subcutaneous injection of corticosterone on depressive-like behaviors with learning and memory impairment in mice...

2022-05-31
【Animal modeling】-The acute toxicity of CKLF1-C19 to Kunming mice

【Animal modeling】-The acute toxicity of CKLF1-C19 to Kunming mice

To study the acute toxicity of the polypeptide CKLF1-C19 of chemokine-like factor 1 (CKLF1) on Kunming mice...

2022-05-31
【Animal modeling】-radioprotective effect of diallyl disulfide on mouse spermatogenic cells

【Animal modeling】-radioprotective effect of diallyl disulfide on mouse spermatogenic cells

To study the radioprotective effect of diallyl disulfide (DADS) on mouse spermatogenic cells...

2022-05-27
【Animal modeling】-Protective effect of Guanxinning tablet on myocardial ischemia-reperfusion injury in rats

【Animal modeling】-Protective effect of Guanxinning tablet on myocardial ischemia-reperfusion injury in rats

To observe the effect of Guanxinning Tablets (GXNT) on myocardial infarction and cardiac autonomic function in rats with myocardial ischemia-reperfusion injury (MI/RI)...

2022-05-27
【Animal Modeling】-Transcranial ultrasound perfusion imaging performance and safety evaluation in rats after skull thinning

【Animal Modeling】-Transcranial ultrasound perfusion imaging performance and safety evaluation in rats after skull thinning

To observe and quantitatively evaluate the performance of right brain transcranial ultrasound perfusion imaging by thinning the local skull of SD rats to improve the acoustic window, and to preliminarily evaluate the effect of bone grinding and trans...

2022-05-27
【Animal Modeling】-A comparative study of in situ liver cancer dynamic imaging and pathology in nude mice

【Animal Modeling】-A comparative study of in situ liver cancer dynamic imaging and pathology in nude mice

To dynamically monitor tumor growth in nude mice after orthotopic liver cancer modeling and to compare it with pathology, so as to determine the appropriate period of intervention therapy...

2022-05-27
【Animal modeling】-Characteristics of liver pathological damage in db/db mice with spontaneous type 2 diabetes

【Animal modeling】-Characteristics of liver pathological damage in db/db mice with spontaneous type 2 diabetes

To dynamically observe the pathological changes and characteristics of the liver of db/db mice with spontaneous type 2 diabetes mellitus, and to provide the basic theory and experimental basis for the experimental study of using the liver of db/db mi...

2022-05-27
【Animal modeling】-The role of phosphokinase Czeta in the anterior cingulate cortex in emotional responses in rats with inflammatory pain induced by Freund\\\\

【Animal modeling】-The role of phosphokinase Czeta in the anterior cingulate cortex in emotional responses in rats with inflammatory pain induced by Freund\\\\

To observe the emotional response of CFA-induced inflammatory pain model rats, and to explore the relationship between the anterior cingulate cortex (ACC) phosphokinase Czeta (PKCzeta) and the emotional response of inflammatory pain rats...

2022-05-27
【Animal modeling】-Effect of Ghrelin on the expression of DKK-1 in the hippocampus and learning and memory function of diabetic rats

【Animal modeling】-Effect of Ghrelin on the expression of DKK-1 in the hippocampus and learning and memory function of diabetic rats

To observe the expression changes of Ghrelin on DKK-1 and WNT signaling pathways in diabetic rats, and to explore the mechanism involved in learning and memory function...

2022-05-27
【Animal Modeling】- Improvement of the method of preventing the displacement of the implanted dilator in the sarcoma and deep fascia of the experimental rabbit

【Animal Modeling】- Improvement of the method of preventing the displacement of the implanted dilator in the sarcoma and deep fascia of the experimental rabbit

To investigate the method of preventing the displacement of the implanted dilator in the sarcoid and deep fascia of rabbits...

2022-05-27
【Animal modeling】-Effect of Bushen Cuovv Decoction on ovarian morphology and sex hormones in polycystic ovary syndrome model rats

【Animal modeling】-Effect of Bushen Cuovv Decoction on ovarian morphology and sex hormones in polycystic ovary syndrome model rats

To explore the effect of Bushen Cuovary Decoction on sex hormone, anti-Müllerian hormone and ovarian morphology in polycystic ovary syndrome model rats, and to explore the treatment of polycystic ovary syndrome (PCOS) by Bushen Cuovvary Decoction mec...

2022-05-27
【Animal modeling】-Effect of astragaloside Ⅱ on IL-21/STAT3 pathway and airway inflammation in juvenile asthmatic rats

【Animal modeling】-Effect of astragaloside Ⅱ on IL-21/STAT3 pathway and airway inflammation in juvenile asthmatic rats

To investigate the effect of astragaloside Ⅱ on interleukin-21 ( IL-21 ) / signal transducer and activator of transcription 3 ( STAT3 ) pathway and airway inflammation in juvenile asthmatic rats...

2022-05-27
【Animal modeling】-PCR detection and analysis of various bacteria in experimental rats and mice

【Animal modeling】-PCR detection and analysis of various bacteria in experimental rats and mice

To investigate the bacterial carriage status of rats and mice in Shanghai laboratory animal production facilities...

2022-05-26