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【Animal Modeling】-A comparative study of in situ liver cancer dynamic imaging and pathology in nude mice

【Animal Modeling】-A comparative study of in situ liver cancer dynamic imaging and pathology in nude mice

To dynamically monitor tumor growth in nude mice after orthotopic liver cancer modeling and to compare it with pathology, so as to determine the appropriate period of intervention therapy...

2022-05-26
【Animal modeling】-Characteristics of liver pathological damage in db/db mice with spontaneous type 2 diabetes

【Animal modeling】-Characteristics of liver pathological damage in db/db mice with spontaneous type 2 diabetes

To dynamically observe the pathological changes and characteristics of the liver of db/db mice with spontaneous type 2 diabetes mellitus, and to provide the basic theory and experimental basis for the experimental study of using the liver of db/db mi...

2022-05-26
【Animal Modeling】-Comparison of Two Staining Methods for Rat Vaginal Smears

【Animal Modeling】-Comparison of Two Staining Methods for Rat Vaginal Smears

To find a simple staining method for determining the four stages of the rat estrous cycle by staining the vaginal smears of SD female rats to observe the cell morphology...

2022-05-26
【Animal modeling】-Establishment and identification of vitamin D receptor gene knockout mouse strain

【Animal modeling】-Establishment and identification of vitamin D receptor gene knockout mouse strain

To explore the optimal breeding method and identification method of vitamin D receptor (VDR) knockout mice, and to provide animal models for further study of VDR function and related diseases...

2022-05-26
【Animal Modeling】-Discussion on the Sequence Scheme of Reducing Image Respiration and Heartbeat Artifacts in In vivo Thoracic Scanning of Rats

【Animal Modeling】-Discussion on the Sequence Scheme of Reducing Image Respiration and Heartbeat Artifacts in In vivo Thoracic Scanning of Rats

To develop a sequence that reduces image breathing and heartbeat artifacts in 256-slice spiral CT rat in vivo chest CT scans...

2022-05-26
【Animal Modeling】-Effect of nicotine on changes of pain threshold plasticity and cardioprotection in rats with myocardial infarction

【Animal Modeling】-Effect of nicotine on changes of pain threshold plasticity and cardioprotection in rats with myocardial infarction

To observe the plastic changes of pain threshold in rats with myocardial infarction, and to explore the effect of nicotine on visceral pain and whether it has a protective effect on ischemic myocardium...

2022-05-26
[Animal Modeling]-Blocking the PD1/PD-L1 pathway mediated by macrophages inhibits the recurrence of tuberculosis in mice

[Animal Modeling]-Blocking the PD1/PD-L1 pathway mediated by macrophages inhibits the recurrence of tuberculosis in mice

Functional PD? Using L1 (programmed cell death ligand 1, PD 2 L1) monoclonal antibody, PD1/PD 3. To study the mechanism of immune intervention and relapse after tuberculosis treatment by blocking the L1 pathway...

2022-05-26
【Animal Modeling】-Effect of psycho-dependent heroin on embryonic development and Bax expression in brain tissue of rats

【Animal Modeling】-Effect of psycho-dependent heroin on embryonic development and Bax expression in brain tissue of rats

To investigate the effect of heroin, a psychotropic substance, on the development of embryonic rats and the expression of Bax in the brain...

2022-05-26
【Animal Modeling】-Effect of a single intraosseous injection of low-dose simvastatin on angiogenesis after myocardial infarction in rats

【Animal Modeling】-Effect of a single intraosseous injection of low-dose simvastatin on angiogenesis after myocardial infarction in rats

To study the effect of intraosseous local single injection of low-dose simvastatin on angiogenesis and cardiac function in rats after myocardial infarction...

2022-05-26
【Animal Modeling】-Effects of IL-27 and its receptors on the proliferation and transformation of lung fibroblasts

【Animal Modeling】-Effects of IL-27 and its receptors on the proliferation and transformation of lung fibroblasts

To investigate the effects of IL-27 and its receptor (WSX-1) on the proliferation, transformation and collagen synthesis of mouse lung fibroblasts induced by TGF-β1...

2022-05-26
【Animal Modeling】-Minocycline inhibits the hyperpolarization-activated current of glial neurons in the dorsal horn of rat spinal cord

【Animal Modeling】-Minocycline inhibits the hyperpolarization-activated current of glial neurons in the dorsal horn of rat spinal cord

To study the effect of minocycline on the hyperpolarization-activated current (Ih) of colloidal (SG) neurons in the spinal dorsal horn of rats...

2022-05-26
【Animal modeling】-Establishment and application of immunocomb detection method for simian immunodeficiency virus antibody

【Animal modeling】-Establishment and application of immunocomb detection method for simian immunodeficiency virus antibody

To prepare the SIV30 protein of simian immunodeficiency virus (SIV) by genetic engineering technology as an antigen diagnostic reagent, and to establish an immunocomb method (IC) for the specific detection of anti-SIV antibody IgG in the serum of exp...

2022-05-25
【Animal Modeling】-Screening of microsatellite primers for experimental marmosets and analysis of genetic diversity

【Animal Modeling】-Screening of microsatellite primers for experimental marmosets and analysis of genetic diversity

To screen and optimize marmoset microsatellite DNA primers for genetic analysis and evaluation of the experimental marmoset population introduced by the Institute of Medical Laboratory Animals, Chinese Academy of Medical Sciences...

2022-05-25
【Animal modeling】-Analysis of biological parameters and cardiac physiological function in mice overexpressing Slit2 gene

【Animal modeling】-Analysis of biological parameters and cardiac physiological function in mice overexpressing Slit2 gene

To measure and evaluate the basic biological parameters, cardiac ultrasound morphology and function, and transcriptome sequencing of human Slit2 gene overexpressing mice (Slit2-Tg mice), so as to provide reference for the application of this mouse in...

2022-05-25
【Animal modeling】-Changes and characteristics of three types of CD molecules and IFN-γ expression in tree shrew infected with reovirus

【Animal modeling】-Changes and characteristics of three types of CD molecules and IFN-γ expression in tree shrew infected with reovirus

To investigate the characteristics of tree shrew reovirus-induced immune changes, and to provide theoretical basis for virus prevention in tree shrew...

2022-05-25
【Animal Modeling】-Transcranial ultrasound perfusion imaging performance and safety evaluation in rats after skull thinning

【Animal Modeling】-Transcranial ultrasound perfusion imaging performance and safety evaluation in rats after skull thinning

To observe and quantitatively evaluate the performance of right brain transcranial ultrasound perfusion imaging by thinning the local skull of SD rats to improve the acoustic window, and to preliminarily evaluate the effect of bone grinding and trans...

2022-05-25