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To establish a cynomolgus monkey model of hyperlipidemia...
2024-10-30To investigate the effect of ligustrazine on extracellular regulated protein kinase pathway in collagen-induced arthritis rats...
2024-10-30Adult rats were anesthetized, with skin incision, muscle dissection, bilateral thyroid separation and excision, and muscle and skin suturing. Observe the general condition of rats, test left ventricular function and thyroid function, euthanize animal...
2024-10-30Macrophages accumulate in adipose tissue, trigger chronic low-grade inflammation, and promote the development of systemic insulin resistance...
2024-10-30Adult rats were anesthetized with ether and bilateral adrenalectomy was performed. After surgery, they were raised in plastic mouse boxes with shavings as bedding, kept at room temperature of 21-25 ℃, and replaced with glucose physiological saline fo...
2024-10-30The response of different animals to cholesterol is completely different, with rabbits being the most sensitive to cholesterol, while rodents (such as mice and rats) have almost no response to cholesterol. In 1908, Ignatowski, a Russian pathophysiolo...
2024-10-30To explore the effect of moderate intensity aerobic exercise on inhibitory Synaptic plasticity of VTA dopamine neurons in nicotine withdrawal mice, so as to provide some experimental evidence for reducing nicotine relapse by exercise...
2024-10-30Functional impairment caused by facial nerve muscle disease and facial nerve injury is common and serious. Aesthetic defects also bring suffering to patients, leading to social isolation and further emotional distress...
2024-10-29Application of UPLC-Q/TOF-MS/MS based on UPLC-Q/TOF-MS/MS urine metabolomics method to screen potential metabolic markers of damp-heat diarrhea and explore damp-heat diarrhea in rats Pathogenesis of diarrhea...
2024-10-29To investigate a method for reducing mortality in a lithium chloride-pilocarpine-induced status convulsive model by gastric gavage with modified oral rehydration salts...
2024-10-29To preliminarily explore the therapeutic effect and possible regulatory mechanism of heme oxygenase inducer hemin (Hemin) in rats with pregnancy-induced hypertension (HDCP)...
2024-10-23To establish a primary culture method of normal knee synovial cells in (SD) rats and a lipopolysaccharide-induced fibroblast-like synovial cell inflammation model...
2024-10-23Adult mice exhibit hemodynamic and clinical signs similar to human HF. Therefore, using gene knockout or transgenic mouse models to alter the expression of heart specific genes, and studying the roles and mechanisms of certain genes in cardiac develo...
2024-10-23To construct the p27 protein of simian D-type retrovirus, and establish a flow immunofluorescence microsphere detection technology for the detection of simian D-type retrovirus...
2024-10-22To compare the hepatotoxicity of matrine and oxymatrine, in order to explore their severity and characteristics of toxicity, and to preliminarily elucidate the toxicity mechanism?...
2024-10-22To investigate the protective or influence of bifidobacteria on liver function in rats with chronic alcoholic liver injury, and to explore its mechanism preliminarily...
2024-10-22