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How to prepare rat sinusitis model?

How to prepare rat sinusitis model?

Directly inject bacteria into the nasal cavity: use adult male rats weighing 200-250g and use a syringe to directly inject a certain amount of bacteria into the rat\'s sinus cavity without blocking the sinus opening after injection. According to expe...

2020-08-08
How to prepare an animal model of allergic rhinitis?

How to prepare an animal model of allergic rhinitis?

Reproduction method In adult male rats weighing 200 to 250 g, 1 mg ovalbumin (EA) and aluminum hydroxide gel are used as adjuvants, injected intraperitoneally, and 100 mg pertussis toxin is collected. Intraperitoneal injection, repeat injection after...

2020-08-08
How to prepare the animal model of basilar artery embolism?

How to prepare the animal model of basilar artery embolism?

Method of reproduction: Inject sodium pentobarbital (35 mg/kg body weight) intraperitoneally into 400-450 g pure white red-eyed guinea pigs for anesthesia, place the head on a special head frame and insert it into the trachea...

2020-08-08
How to prepare an animal model of peripheral vestibular damage?

How to prepare an animal model of peripheral vestibular damage?

  Reproduction method When the rat weighs about 200 g and the guinea pig weighs about 500 g, the external auditory canal is clean, the eardrum is intact, there is no spontaneous nystagmus, and the hearing is sharp....

2020-08-08
How to prepare an animal model of autoimmune inner ear disease?

How to prepare an animal model of autoimmune inner ear disease?

Replication method 4-week-old inbred male C57BL/6 mice and guinea pigs weighing 300 to 400 g exhibited normal ear reflex and no middle ear infection. After the guinea pig is anesthetized, the heart is perfused, the temporal bone is decapitated, all i...

2020-08-08
How to prepare an animal model of neurological deafness?

How to prepare an animal model of neurological deafness?

A variety of healthy general-grade guinea pigs, male or female, weighing 400-500 g, sensitive to ear reflexes, and otoscope examination ruled out inflammation of the outer and middle ear...

2020-08-08
How to prepare an animal model of otitis media?

How to prepare an animal model of otitis media?

The replication method uses 300-420 g guinea pigs and reflects players normally. First, perform an otoscope examination to check for external and middle ear diseases. Exclude and test separately...

2020-08-08
How to prepare an animal model of orbital fracture with invaginated eyeball?

How to prepare an animal model of orbital fracture with invaginated eyeball?

Breeding method Anesthetize adult cats weighing 2.0 to 3.0 kg by intramuscular injection of 20 mg/kg body weight of ketamine and 2.5 mg/kg disi epa...

2020-08-08
Shìwǎngmó xīnshēng xiěguǎn dòngwù móxíng zěnme zhìbèi? 16/5000 How to prepare an animal model of retinal neovascularization?

Shìwǎngmó xīnshēng xiěguǎn dòngwù móxíng zěnme zhìbèi? 16/5000 How to prepare an animal model of retinal neovascularization?

C57BL/6N mice born 7 days after birth were placed in a 75% oxygen environment, kept at room temperature (23±2) ℃, and returned to the air environment after 5 days...

2020-08-08
How to prepare an animal model of retinal vein occlusion?

How to prepare an animal model of retinal vein occlusion?

Copy method Anesthetize 8-10 kg piglets by intramuscular injection of 0.1 ml/kg of compound ketamine, use compound troponin to dilate pupils and fix the head on the head...

2020-08-08
【Animal model】-animal model of traction retinal detachment

【Animal model】-animal model of traction retinal detachment

Replication method (1) Culture of rabbit skin fibroblasts: Cut a New Zealand rabbit weighing about 2 kg into 1 piece, disinfect the skin with 75% ethanol, and use cornea quhuaning to cut into the dermis to a diameter of 8 mm incision...

2020-08-08
[Dòngwù móxíng]-kǒng yuán xìng shìwǎngmó tuōlí dòngwù móxíng 19/5000 【Animal model】-animal model of rhegmatogenous retinal detachment

[Dòngwù móxíng]-kǒng yuán xìng shìwǎngmó tuōlí dòngwù móxíng 19/5000 【Animal model】-animal model of rhegmatogenous retinal detachment

Reproduction method: No abnormality in eye examination. Fixed New Zealand rabbits weighing 2.0-2.5 kg, flushed with 1% atropine eye drops to dilate the pupils, and 30 mg per mg was injected into the tail vein of the ear to anesthetize the kilogram of...

2020-08-08
[Animal model]-Optic nerve stretch injury model

[Animal model]-Optic nerve stretch injury model

Reproduction method Inject pentobarbital sodium with a body weight of 30 mg/kg body weight into a guinea pig weighing about 700 g, incise the outer edge under an operating microscope, cut the corneal limbus into 360°, cut the conjunctiva and eyeball...

2020-08-08
【Animal model】-Chemical substance induced cholecystitis model

【Animal model】-Chemical substance induced cholecystitis model

Reproduction method Male and female guinea pigs weigh 300-400 grams, weigh 60-kg/kg body weight, once a day, inject lincomycin hydrochloride or 300 mg/kg body weight lithocholic acid intraperitoneally for 7 consecutive days (every day for 15 consecut...

2020-08-07
How to prepare an animal model of liver failure induced by multiple factors?

How to prepare an animal model of liver failure induced by multiple factors?

Replication method Adult male mice or rats 12 hours after fasting, intraperitoneal injection of D-galactosamine (D-Gal) and endotoxin lipopolysaccharide (LPS) 0.1 at a dose of 800-1000 mg/kg body weight mg/kg Body weight: or adult rats, 30 mg/kg body...

2020-08-07
[Animal Experiment]-Phytolithic cholecystitis model

[Animal Experiment]-Phytolithic cholecystitis model

Reproduction method Inject 3% sodium pentobarbital intravenously to male or female rabbits weighing 2-3kg at a dose of 30mg/kg body weight and use sterile drape anesthesia under the xiphoid...

2020-08-07