[Animal Modeling] - Establishment and Evaluation of a Constipated Irritable Bowel Syndrome Model with Liver Depression Syndrome

To prepare rat models of liver depression syndrome with constipation type irritable bowel syndrome using single factor modeling method and multi factor combined modeling method, and to provide an ideal IBS-C experimental animal model by comparing dif...

2024-03-13

【Animal Modeling】-Research progress on artificially assisted reproductive technology and genetic modification models of marmosets

The common cotton-eared marmoset is a small non-human primate experimental animal. It has the advantages of low feeding cost, high reproductive efficiency, and short sexual maturity. It is very suitable for assisted reproductive technology and geneti...

2024-03-13

【 Animal Modeling 】 - Evaluation of Syndrome in a Tidal Heat Model Rat Induced by Bilateral Ovariectomy and Tamoxifen Administration

To explore a syndrome animal model for studying women\'s hot flashes...

2024-03-13

[Animal modeling] Research progress in evaluation of animal models of type 2 diabetes peripheral neuropathy

Diabetes peripheral neuropathy is one of the common complications of diabetes. at present, the understanding of its pathogenesis is not clear enough, and there is a lack of effective treatment methods...

2024-03-13

[Animal Modeling] - Metabolomics Analysis of Tree Shrew Breast Tumor Model

To study the changes in metabolomics during the occurrence and development of breast tumors in tree shrews, explore the close relationship between changes in metabolic substances in the body and tumor occurrence and development, and screen for biomar...

2024-03-13

[Animal modeling]- construction and evaluation of a mouse model of acute hypoxia induced intestinal stress injury at high altitude

To establish an experimental high-altitude mouse intestinal stress injury model by simulating an acute hypoxic environment, laying a foundation for exploring the pathogenic mechanism and prevention and treatment measures of high-altitude acute gastro...

2024-03-13

[Animal modeling]- Acute obstructive suppurative cholangitis animal model

Wistar rats; Drug: 011184 type Escherichia coli, 1% pentobarbital; Instrument: Surgical microscope...

2024-03-12

[Animal modeling]- Animal model of guinea pig gallstones induced by lithogenic feed

Female guinea pigs, weighing 250-300g; Medication: Stone feed (formula: add 1.5% sucrose, 1% casein, 1% lard, 1% cellulose, 0.02% bile acid, and 0.05% cholesterol to the basic food)...

2024-03-12

[Animal modeling] - High sugar diet induced gallstone animal model

Syrian hamsters, weighing around 50-60g; Medication: High sugar bait (formula: sucrose 74%, casein 21%, salt 4.4%, choline 0.1%, concentrated fish liver oil 0.5%)...

2024-03-12

【Animal modeling】 - bile duct cyst animal model

sheep or goats (within 14 days after birth), regardless of gender; Medication: pentobarbita...

2024-03-12

【Animal Modeling】-Comparison of Two Staining Methods for Rat Vaginal Smears

To find a simple staining method for determining the four stages of the rat estrous cycle by staining the vaginal smears of SD female rats to observe the cell morphology...

2024-03-12

【Animal Modeling】-Effect of Guiji Cream on fibronectin and basic fibroblast growth factor in a rat model of stage III pressure ulcer

The purpose of this study was to investigate the effect of Guiji cream on the levels of fibronectin and basic fibroblast growth factor in pressure ulcer granulation tissue in pressure ulcer model rats...

2024-03-12

[Animal modeling] - Zhenqi Fuzheng Granule inhibits angiogenesis in liver cancer model rats through miR-200c/ZEB pathway

To explore the inhibitory effect of Zhenqi Fuzheng Granule on angiogenesis in rat model of liver cancer and its possible mechanism...

2024-03-12

【Animal Modeling】-miR-144 negatively regulates the expression of TOLL-like receptor 2 in rat macrophages

To clarify the relationship between the effects of TOLL-like receptor 2 (TLR2) and microRNA144 (miR-144)...

2024-03-12

【Animal Modeling】-Mice model of lung metastasis and postoperative recurrence after bone marrow injection

Establish a model of bone marrow injection for the treatment of lung metastasis and postoperative recurrence, clarify the superiority and feasibility of the model established by bone marrow injection, and provide a new research basis for the study of...

2024-03-11

[Animal modeling] - Obesity model of small pigs induced by high sugar and high-fat diet

To investigate the effect of high fat and high sugar diet on fat distribution and blood biochemical indexes in Bama miniature pigs...

2024-03-11