【Animal modeling】-Effect of knockout TRPC6 on MPTP-induced neuroinflammatory injury in mice

To detect the expression of TRPC6 channel in microglia in a mouse MPTP-induced neuroinflammation model, and to explore the effect of TRPC6 channel on inflammatory expression and dopaminergic neuron damage...

2024-03-01

[Animal modeling] Anesthetic effect of compound doses of Shutai and Lumianning on Bama miniature pigs

To study the anesthetic effect of Shutai and Lumianning combined anesthesia on Bama mini pigs, and to observe the effect of anesthesia on physiological indexes of mini pigs...

2024-03-01

【Animal Modeling】-Comparison of Two Hepatitis B Hepatitis B Fibrosis Mouse Compound Models

To use C57BL/6N-Tg(1.28HBV)/Vst hepatitis B virus transgenic mice and rAAV8-1.3HBV adeno-associated virus-transfected mice combined with CCl4 intraperitoneal injection to induce hepatitis B fibrosis mouse model, and compare the two mice Virological a...

2024-03-01

【Animal Modeling】-Depression-like behavioral changes in male and female rats induced by restraint stress of different durations

To investigate the effects of chronic restraint stress of different restraint durations on the depression-like behavior of male and female SD rats, and to provide a basis for the selection of experimental animals\\\\\\\' gender and experimental durat...

2024-03-01

[Animal modeling] - Construction and evaluation of two models of obese polycystic ovary syndrome with insulin resistance in rats

To establish an animal model of obese polycystic ovary syndrome (PCOS) with insulin resistance by two different ways combined with high-fat diet, and compare its endocrine and metabolic characteristics...

2024-03-01

【Animal modeling】-Comparative study on bone growth in rats after long-term exposure to low-fluoride aluminum and short-term high-fluoride aluminum exposure

To observe the effects of different doses of fluoride and aluminum combined with the duration of intake on longitudinal bone growth and bone metabolism in rats...

2024-02-29

【Animal modeling】-Behavioral differences in learning and memory ability of C57BL/6J, BALB/c, ICR strain mice

To compare the behavioral differences of learning and memory ability of C57BL/6J, BALB/c and ICR strain mice...

2024-02-29

【Animal modeling】-The expression and ultrastructural observation of kidney-yang deficiency-related mRNA in the hypothalamus of Lewis rats

To further study the kidney-yang deficiency constitution of Lewis rats by observing the gene expression and ultrastructure related to kidney-yang deficiency in the hypothalamus of Lewis rats...

2024-02-29

【 Animal Modeling 】 - Optimization of modeling method for primary liver cancer in mice

To establish a good, fast, and stable mouse primary liver cancer model...

2024-02-28

[Animal modeling] - Establishment of a rabbit model of chronic salpingitis induced by Escherichia coli

To establish a chronic inflammation model of the fallopian tubes in New Zealand rabbits using Escherichia coli...

2024-02-28

[Animal modeling] - Establishment of atherosclerotic model of combination of phlegm and blood stasis disease and syndrome in rats and intervention study of prescriptions and drugs

To establish an atherosclerotic model of phlegm and blood stasis in rats, and observe the changes of inflammatory factors in the model rats and the intervention effect of the prescription (Danlou Tablet)...

2024-02-28

[Animal modeling] - exploration of the stability of a rat model of acute subdural hematoma induced by blood injection volume

To explore the effect of different volumes of autologous blood on the stability of a rat model of subdural hematoma...

2024-02-28

[Animal Modeling] - Establishment of Calcitonin Gene Related Peptide Transgenic Mice and Dynamic Analysis of Blood Pressure

To establish calcitonin gene related peptides α and β Transgenic mice were used to dynamically compare and analyze their blood pressure, and an animal model suitable for hypertension research was established...

2024-02-28

【 Animal Modeling 】 - Correlation Analysis of Evaluation Methods for Focal Cerebral Ischemia Models in Rats

To analyze the correlation between three successful methods of preparing a rat model of middle cerebral artery occlusion using thread occlusion method, and provide a new method and standard for evaluating the model...

2024-02-28

[Animal Modeling] - Establishment of a Rabbit Sinus Node Injury Model Induced by Formaldehyde

To establish a formaldehyde induced rabbit sinoatrial node injury model...

2024-02-28

[Animal modeling] - constructing a large-scale neurodegenerative disease animal model using CRISPR

Animal models are very valuable in helping us understand the pathogenesis of neurodegenerative diseases and find treatment methods...

2024-02-28